Protein Alignment wek and Zfp335

DIOPT Version :9

• Sequence 1: NP_001260472.1
• Gene: wek / 48785
• FlyBaseID: FBgn0001990
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001093956.2
• Gene: Zfp335 / 259270
• RGDID: 628751
• Length: 1336
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 123/506 - (24%)
• Similarity: 175/506 - (34%)
• Gaps: 184/506 - (36%)

  Fly    70 DSVSKVQAIFELLRHS-------EPQDSQDLDALRLEYGLP--------PACKQDLEFLDIDDTE 119
            |.:....||.:|...|       ||:..|    |||:...|        |...:.|..|:..|..
  Rat   310 DDIVDAGAIDDLEEDSDYNPAEDEPRGRQ----LRLQRPTPSTLRPRRRPGRPRKLPRLETSDLH 370

  Fly   120 DRCSLVEELTISDHSTSPSP---DFEAQTVRTRANLKQCNSDPKVLASPTASIPEVETKRSRRQQ 181
            |.   :.|..:|..||...|   |.||.:          :||.:.|......:  |||
  Rat   371 DG---IGEPLVSSQSTQSPPELQDLEAPS----------SSDLRALGKVGRGL--VET------- 413

  Fly   182 FAAKRNSKVYTATESDDEEAILD-EDEAVSPPPLKRKRGRPKGSGKQKNVDDSDNVTSREPDDNA 245
                      ..::||.|.|... :|||..||   |:||||                ||......
  Rat   414 ----------GVSQSDAENAAPSCQDEADVPP---RRRGRP----------------SRRFLGKK 449

  Fly   246 KSKQDDKTSELSMSPHGSQSSNFVDYPCKICNETFMSFMALRRH--------------------- 289
            ..|...|:.:..:.|          |.|:||...|:|...||.|
  Rat   450 YRKYYYKSPKPLLRP----------YLCRICGSRFLSHEDLRFHVNSHEAGDPQLFKCLQCSYRS 504

  Fly   290 ------KHDM--HGGPKKYVCDHCGKGLKTFTS-----LVEHQLVHTEEK-------PCI----C 330
                  |..|  |.|.|.|.||.|     ::||     ::.|..||::::       |.:    |
  Rat   505 RRWSSLKEHMFNHVGSKPYKCDEC-----SYTSVYRKDVIRHAAVHSQDRKKRPDPTPKLSSFPC 564

  Fly   331 PVCNAGFKNKARLRVHSQTHG-EPKFECNVCGKKLQTRAILNKHKYVHTD---ERRFKCEVCGSG 391
            |||...:..:.||..|.:||. |....|:.|||..:.|.....|...|..   .||||||.|...
  Rat   565 PVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANRRFKCEFCEFV 629

  Fly   392 CKNSTALKIHLLG-----------------------------HTGLRPYVCKYCGKAFASNTNCR 427
            |::..||..|.|.                             |||.:|:.|:||..:.....|.|
  Rat   630 CEDKKALLNHQLSHVSDKPFKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLR 694

  Fly   428 SH----------KW-KKHPELASKEDETESSRVPVPTLEELRAITREMAKA 467
            .|          :| ::|||      |..|.|.|..:|:::..:.::.:.|
  Rat   695 LHVRCRHANSFEEWGRRHPE------EPPSRRRPFFSLQQIEELKQQHSAA 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wek	NP_001260472.1	zf-AD	11..80	CDD:214871	3/9 (33%)
		C2H2 Zn finger	273..294	CDD:275368	10/49 (20%)
		C2H2 Zn finger	302..322	CDD:275368	6/24 (25%)
		C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	385..405	CDD:275368	8/48 (17%)
		zf-H2C2_2	397..422	CDD:290200	11/53 (21%)
		C2H2 Zn finger	413..429	CDD:275368	5/15 (33%)
Zfp335	NP_001093956.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..222
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..398		25/104 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..442		14/45 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	732..766		1/8 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	961..1013

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930