Protein Alignment Mtr4 and EMB25

DIOPT Version :10

• Sequence 1: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_177164.1
• Gene: EMB25 / 843343
• AraportID: AT1G70070
• Length: 1171
• Species: Arabidopsis thaliana
• Alignment Length: 1152
• Identity: 300/1152 - (26%)
• Similarity: 480/1152 - (41%)
• Gaps: 256/1152 - (22%)

  Fly    49 KEATSSKGAEGDDKGDVTEEPTKRLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIVT 113
            :|....:..|.:|..|...:....:..|   :...||::.|:|...::|:...:..|.:..|  .
plant    65 EEDDEEEEEEDEDDDDEAADEYDNISDE---IRNSDDDDDDEETEFSVDLPTESARERVEFR--W 124

  Fly   114 HLLDAPKSCTHEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAG 178
            ..::..:|...:...    |.|.:.....:    |.|.:|.|||.||.......||:|||.||:|
plant   125 QRVEKLRSLVRDFGV----EMIDIDELISI----YDFRIDKFQRLAIEAFLRGSSVVVSAPTSSG 181

  Fly   179 KTVVAEYAIAKSLAAKQRVIYTTPIKALSNQKFREFTDEFKD--VGLVTGDVTINPSASCLIMTT 241
            ||::||.|...::|..:|:.||||:|||||||||||.:.|.|  |||:|||..||..|..:||||
plant   182 KTLIAEAAAVSTVAKGRRLFYTTPLKALSNQKFREFRETFGDDNVGLLTGDSAINKDAQIVIMTT 246

  Fly   242 EILRNMLYR-------GSEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIP 299
            ||||||||:       |:.:. .|..:|.||:||:.|..||.||||.:|..|..|:.:.||||:.
plant   247 EILRNMLYQSVGMASSGTGLF-HVDAIVLDEVHYLSDISRGTVWEEIVIYCPKEVQLICLSATVA 310

  Fly   300 NARQFAEWVCHLHKQPCHVVYTDYRPTPL------QHYIFPAGGDGIHLIVDEKG----QFKEDN 354
            |..:.|.|:..:|.: ..:|.:..||.||      :|.:.|        ::||||    :....|
plant   311 NPDELAGWIGEIHGK-TELVTSTRRPVPLTWYFSTKHSLLP--------LLDEKGINVNRKLSLN 366

  Fly   355 FTTAMAVLANAGEAGKGDQKGR---HGGIKGTN---------AGQTNIFKI----VKMIME---- 399
            :....|..|...:...|.:|.|   .||....|         ..:..|.||    |..|.:
plant   367 YLQLSASEARFRDDDDGYRKRRSKKRGGDTSYNNLVNVTDYPLSKNEINKIRRSQVPQISDTLWH 431

  Fly   400 ---RNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLTEEDRRL-PQV--E 458
               :|..|.|.|.|:::.|:. |:|..       :..:|:|:...:.:::..::.|.| |..  |
plant   432 LQGKNMLPAIWFIFNRRGCDA-AVQYV-------ENFQLLDDCEKSEVELALKKFRVLYPDAVRE 488

  Fly   459 NVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFTAPRKFDGK 523
            :....|.|||..||.|.||:.|..||.||..||:|.:|||||.|.|:||||||.:.::..|..|.
plant   489 SAEKGLLRGIAAHHAGCLPLWKSFIEELFQRGLVKVVFATETLAAGINMPARTAVISSLSKKAGN 553

  Fly   524 KFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPINSAFHLTYNMVLN 588
            :...:...|..||||||||||:|:||..:|:............:|.....|:.|.|..:|.||||
plant   554 ERIELGPNELYQMAGRAGRRGIDEKGYTVLVQTAFEGAEECCKLVFAGVKPLVSQFTASYGMVLN 618

  Fly   589 LLRVEEI--------------------NPEYMLERSF--YQFQN-----QAALPGLHDQVEQKTL 626
            |:...::                    ..:.::|:||  |...|     :..|..:.:::|..:.
plant   619 LVAGSKVTRKSSGTEAGKVLQAGRSLEEAKKLVEKSFGNYVSSNVTVAAKQELAEIDNKIEILSS 683

  Fly   627 ELNK----------LTIKDEHNIASY-HHIRSQLDQHGKQFRQW------ITKPQYLLPFLQPGR 674
            |::.          |:.:|...|... ..:|.:..:..:|.|:.      ..||  ||..::.|.
plant   684 EISDEAIDKKSRKLLSARDYKEITVLKEELREEKRKRAEQRRRMELERFLALKP--LLKGMEEGN 746

  Fly   675 L------VKVAAGSQEYDWGIVLNFKKQDQSRK--NPLKAEPSVTIDVLLHVSEAAAKTGDTEPC 731
            |      .|.:.|.::....:.|......|..|  ..:..:.|..::::  ..|.||    .||.
plant   747 LPFICLEFKDSEGREQSVPAVYLGHIDSFQGSKLQKMMSLDESFALNLI--EDELAA----DEPG 805

  Fly   732 KPNERGCMEVVPVAHTLITQISS------------IRVYFPN---DLRSADNRRAVLKTIQEAKK 781
            |||      |.|..:..:...:|            .|..|||   .|..|..|..:...:.:|..
plant   806 KPN------VKPSYYVALGSDNSWYLFTEKWVRTVYRTGFPNIALALGDALPREIMKNLLDKADM 864

  Fly   782 R-----------------------FPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLH 823
            :                       :.|..|||:.:.|                      |:..||
plant   865 QWDKLAESELGSLWRLEGSLETWSWSLNVPVLSSLSD----------------------EDEVLH 907

  Fly   824 KSPELERIHRRYQD----------KVTLQKQLQDLKAELKAAR-SLLQMDELKHR-KRVLRRMGY 876
            .|.|.:...::|::          |::..:..::.|..|:.|. ::.:|..||.| :|::.|:..
plant   908 MSEEYDNAAQKYKEQRSKISRLKKKMSRSEGFREYKKILENANLTVEKMKRLKARSRRLINRLEQ 972

  Fly   877 CKPGDVIEFK----------------------GRVACELSSADELLMTEMIFNGVFNDLTAPQAV 919
            .:|....:|.                      |..|..:...:||.:..::.|....||..||..
plant   973 IEPSGWKDFMRISNVIHESRALDINTHLIFPLGETAAAIRGENELWLAMVLRNKALVDLKPPQLA 1037

  Fly   920 ALLSCFVCDEKSSESVK-----SATELSGPLRSMQDLARRIA-KVSTECKLDLDADTYVDKFKPF 978
            .     ||....||.:|     ....:..|..::.|:...:. :.|:..||....:..:    |.
plant  1038 G-----VCASLVSEGIKVRPWRDNNYIYEPSDTVVDMVNFLEDQRSSLIKLQEKHEVMI----PC 1093

  Fly   979 LMDV-----VLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQM 1020
            .:||     |.||..|.|:..:.....:.||.:.|.:||..:||.|:
plant  1094 CLDVQFSGMVEAWASGLSWKEMMMECAMDEGDLARLLRRTIDLLAQI 1140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	285/1056 (27%)
EMB25	NP_177164.1	Dob10	146..1168	CDD:443638	285/1062 (27%)
		COG2433	<668..>735	CDD:441980	9/66 (14%)