Protein Alignment Mtr4 and Mtrex

DIOPT Version :10

• Sequence 1: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_082427.1
• Gene: Mtrex / 72198
• MGIID: 1919448
• Length: 1040
• Species: Mus musculus
• Alignment Length: 1065
• Identity: 665/1065 - (62%)
• Similarity: 819/1065 - (76%)
• Gaps: 44/1065 - (4%)

  Fly     4 EELFDCFDEVTPSVPPPALNQEEK----PSGSSASKKGNKRQADGTTASKEATSSKGAEGDDKGD 64
            :|||..|::.:.|......::|::    |.| ||.|.|.:..   |....|:.|.    |.:|.|
Mouse     7 DELFSVFEDDSTSAAGAKKDKEKEKWKGPPG-SADKAGKRLD---TKLQSESASG----GKNKRD 63

  Fly    65 VTEEPTKRLKQEASTVAVDDDNNADDEP-----TRTLD-IDDSATLEALRTRIVTHLLDAPKSCT 123
            :..|.|                   |||     .|..| |::..:|..|..|:....::..:.||
Mouse    64 LDVEGT-------------------DEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEGCT 109

  Fly   124 HEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYAIA 188
            ||||...|::||||||..|..||||||:||.|||:||.|:||:|||||||||||||||.||||||
Mouse   110 HEVALPADEDYIPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIA 174

  Fly   189 KSLAAKQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRGSE 253
            .:|..|||||:|:|||||||||:||..:||:||||:||||||||:||||:|||||||:|||||||
Mouse   175 LALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSE 239

  Fly   254 IMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHV 318
            :||||.||:|||||||||.|||||||||:|||||||.|||||||||||||||||:||||||||||
Mouse   240 VMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHV 304

  Fly   319 VYTDYRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGGIKGT 383
            :||||||||||||||||||||:||:|||.|.|:||||.|||.||.:||:..|||||||.||.|
Mouse   305 IYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTK-- 367

  Fly   384 NAGQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLT 448
              |.:|:||||||||||||.|||||||||||||.||:||.||||||.:|||:|:||||||:|.|:
Mouse   368 --GPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLS 430

  Fly   449 EEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVL 513
            :||::|||||:|||||:||||||||||||||||||||||.||||||||||||||||:||||||||
Mouse   431 DEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVL 495

  Fly   514 FTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPINSA 578
            ||..||:|||.||||||||||||:|||||||:||:||||||:|||:||.:|:.:::|.|||:|||
Mouse   496 FTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA 560

  Fly   579 FHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIASYH 643
            ||||||||||||||||||||||||:||||||:..|:||:.::|:....:.||:.|.:|.|:..|:
Mouse   561 FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYY 625

  Fly   644 HIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQEYDWGIVLNFKKQDQSRKNPLKAEP 708
            .||.||.:.||:..::|.||:|.||||||||||||.....::.||:|:||.|:...:.|..:.:|
Mouse   626 KIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDP 690

  Fly   709 SVTIDVLLHVSEAAAKTGDTE---PCKPNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADNRR 770
            ...::|||..|:.:.|...||   |.||:|:|.|:||||...|::.||::|:|.|.|||..|||:
Mouse   691 LYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQ 755

  Fly   771 AVLKTIQEAKKRFPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRRY 835
            :|||:|||.::|||.|.|:|:|||||.|:|:..:.::..:..||.|:..||||..|.||.::...
Mouse   756 SVLKSIQEVQRRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLC 820

  Fly   836 QDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADELL 900
            :.|..:...::..|.|||.||::|||||||.|||||||:|:....||||.|||||||:|||||||
Mouse   821 ERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELL 885

  Fly   901 MTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTECKLD 965
            :|||:|||:||||::.||.|||||||..|.|||..|...:|:||||.||:.|:||||||.|.||:
Mouse   886 LTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLE 950

  Fly   966 LDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIGNT 1030
            :|.:||:..|||.|||||..|..|::|..:|||||:||||||||||||||||||||||:|.||||
Mouse   951 IDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNT 1015

  Fly  1031 DLENKFSEGIRLLKRDIVFAASLYL 1055
            :|||||:|||..:||||||||||||
Mouse  1016 ELENKFAEGITKIKRDIVFAASLYL 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	613/905 (68%)
Mtrex	NP_082427.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..77		19/87 (22%)
		Dob10	125..1012	CDD:443638	600/890 (67%)
		DEIH box	250..253		2/2 (100%)