Protein Alignment Mtr4 and skiv2l

DIOPT Version :9

• Sequence 1: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: XP_005170104.1
• Gene: skiv2l / 559653
• ZFINID: ZDB-GENE-010430-5
• Length: 1249
• Species: Danio rerio
• Alignment Length: 1134
• Identity: 389/1134 - (34%)
• Similarity: 579/1134 - (51%)
• Gaps: 181/1134 - (15%)

  Fly     1 MDIEELFDCFDEVTPSVPP--------------PALNQEE----KPSGSSASKKGNKRQADGTTA 47
            :::..|...||:|..:.|.              |..|..|    |.||||        |..|.|
Zfish   215 VNLLSLLSTFDDVLDAPPEDKEGVSQKEEIVKLPRTNSLEDLGIKDSGSS--------QPQGNT- 270

  Fly    48 SKEATSSKGAEGDDKGDVTEEPTKRLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIV 112
                           |.:||:..|.|::|..           |.....:.:|.|:.......||
Zfish   271 ---------------GSLTEQKKKNLEEEKG-----------DNKKWAIPVDISSPCADFYKRI- 308

  Fly   113 THLLDAPKSCTHEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSA 177
                             ||            ||.:|||.||.||:||||.::...||.|:|||||
Zfish   309 -----------------PD------------PAFKYPFELDVFQKQAILRLEAHDSVFVAAHTSA 344

  Fly   178 GKTVVAEYAIAKSLAAKQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTE 242
            |||||||||||.|.....|.|||:|||||||||||:|.:.|.||||:||||.:||..||||||||
Zfish   345 GKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKNTFGDVGLLTGDVQLNPEGSCLIMTTE 409

  Fly   243 ILRNMLYRGSEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEW 307
            |||:|||.|||::|::.||:|||:||:.|.||||||||.||:||::|..:.||||:|||.:|:||
Zfish   410 ILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNAVEFSEW 474

  Fly   308 VCHLHKQPCHVVYTDYRPTPLQHYIFPAGG----DGIHLIVDEKGQFKEDNFTTAMAVLANAGEA 368
            :..:.|:..:|:.|..||.||:||::....    ..:.:::|..|.|....:..|:       ||
Zfish   475 IGRIKKRHIYVISTIKRPVPLEHYLYTGNSTKTQKELFMLLDATGNFLTKGYYAAV-------EA 532

  Fly   369 GKGDQKGRHGGIKGT-NAGQTNIF---------KIVKMIMERNFAPVIIFSFSKKDCEIYAMQMA 423
             |.::..:|....|| |..|.|..         .::..:.:|...||:.|:||:..|:..|..:.
Zfish   533 -KKERTSKHAQSFGTKNVSQHNTTASQDRAVWQTLLNYLSQRQQTPVVAFTFSRTRCDENARSLT 596

  Fly   424 KLDFNTPDEKKLVDEVFNNAMDVLTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFG 488
            .||..|..||..:......::..|...||:|||:..:..||:||||:||.|:||||||.||:||.
Zfish   597 SLDLTTSIEKSEIHSFLQKSLTRLRGGDRQLPQILLMRDLLKRGIGVHHSGILPILKEVIEMLFS 661

  Fly   489 EGLIKALFATETFAMGLNMPARTVLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVIL 553
            .||:|.||||||||||:|||||||:|.:.||.||..||.:..||||||||||||||||..|.||:
Zfish   662 RGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVII 726

  Fly   554 MIDEKVSPAVG--RDIVQGKADPINSAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPG 616
            :....|.. :|  ..::.||...::|.|.|||.|:|||||||.:....|::|||  .:|......
Zfish   727 LCKAGVHD-MGELHSMMLGKPTVLHSQFRLTYTMILNLLRVEALRVTDMMKRSF--SENHRDTQA 788

  Fly   617 LHDQVEQKTLELNKLTIKDEH----NIASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVK 677
            ...::.:....|:.|...|..    ::.||:|..::|....:..:|.:.:....|..|..||:|.
Zfish   789 HEKRISELRNTLSSLPPLDTEGQLSDLLSYYHTITELHITTQSLQQAVLESVNGLKALSVGRVVI 853

  Fly   678 VAAGSQEYDWGIVLNFKKQDQSRKNPLKAEPSVTIDVLLHV----SEAAAKTGDTEPCKPNERGC 738
            |.........|::|.......:|          |...|:..    .|||:.....:...|.....
Zfish   854 VNNSQHHNSLGVILQVSSDAVNR----------TFTALIICEKGNEEAASDEQSNKVALPIYSKT 908

  Fly   739 MEVV--PVAHTL----ITQISSIRV----YFPNDLRSADNRRAVLKTIQEAKKRFPLGPP----- 788
            :.:.  |.:||:    :..||:|..    ..|..:....|:|        .:.||.|.||
Zfish   909 LFIPEGPCSHTVQKLKLQDISAITTKALKVIPERIIDNYNKR--------LQPRFRLDPPGQAIS 965

  Fly   789 ------------------VLNPIDDMNIKDREFRDIVNTISQFEKRLEE-----HPLHKSPELER 830
                              ||:|::|:::|.   .|:|..:.: ::.|::     |.:| ||....
Zfish   966 TATQELLRLAEANMGGMTVLDPVNDLHLKG---VDVVEGVMR-QRVLQDSLKDFHCIH-SPTFSE 1025

  Fly   831 IHRRYQDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSS 895
            ...|.|:::::|::|..| ..|.:.:||..:.|...|.:||..:.|......::.||||||::||
Zfish  1026 QFTRVQERMSVQEELDKL-LFLVSDQSLTLLPEYHQRIKVLEALQYVDSSGAVQLKGRVACQISS 1089

  Fly   896 ADELLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVST 960
             .|||:||::|....:.|...::.|||||.|..:.:.........|...:..:..:|:||..:..
Zfish  1090 -HELLLTELLFENTLSPLAPEESAALLSCLVFTQNTQIEPHITNTLQEGINQVLAVAQRIGDLQR 1153

  Fly   961 ECKLDLDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASK 1025
            :|.:...|:.:|.:||..|.:||..|.:|..|..:.::||:.||:|:||::||:|:|:::.||::
Zfish  1154 DCGIAQTAEDFVAQFKFGLTEVVYCWARGMPFAEIAQLTDVQEGTIVRCIQRLDEVLKEVRQAAR 1218

  Fly  1026 TIGNTDLENKFSEGIRLLKRDIVFAASLY 1054
            .:|::.|.:|.......::|||||.||||
Zfish  1219 IVGDSVLGSKMERASLAIRRDIVFTASLY 1247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	91..1055	CDD:226947	366/1026 (36%)
		DEAD	154..299	CDD:278688	96/144 (67%)
		HELICc	390..554	CDD:238034	84/172 (49%)
		rRNA_proc-arch	600..853	CDD:289976	59/298 (20%)
		DSHCT	881..1048	CDD:285374	54/166 (33%)
skiv2l	XP_005170104.1	Dob10	299..1247	CDD:226947	362/1013 (36%)
		DEAD	323..470	CDD:278688	98/146 (67%)
		HELICc	632..717	CDD:197757	58/84 (69%)
		rRNA_proc-arch	774..1048	CDD:289976	60/299 (20%)
		DSHCT	1075..1241	CDD:285374	54/166 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4581
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D176060at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100340
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720