Protein Alignment Pgant35A and Galnt14

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_082140.2
• Gene: Galnt14 / 71685
• MGIID: 1918935
• Length: 550
• Species: Mus musculus
• Alignment Length: 588
• Identity: 225/588 - (38%)
• Similarity: 309/588 - (52%)
• Gaps: 97/588 - (16%)

  Fly    18 LVAVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTPNASITTGESPAAPK 82
            :..|:|:..|||:            |      .|.|               ...:..|.....||
Mouse    12 IFGVLWITVLLFF------------W------VTKR---------------KLEVPLGPEVQTPK 43

  Fly    83 PPSDP------EQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQET 141
             |||.      ||.:....:..|:.: :.|..||.:|||...|..|...||:||||||.|..  .
Mouse    44 -PSDADWDDLWEQFDERRYLNAKKWR-VGDDPYKLYAFNQRESERISSNRAVPDTRHKRCSL--L 104

  Fly   142 TEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRAR 206
            ....:||..||::.|:||.:.||:|:|::||.|||.:|::|||||||.|:.||       |.:..
Mouse   105 VYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPE-------DCKQL 162

  Fly   207 LKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPV 271
            :|...::.::|.:|:||:|||:.||..|.|..|.|||||.|||:.||:|||..:|.:...:..||
Mouse   163 IKLPKVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPV 227

  Fly   272 IDLINADTFEYTPSPL-VRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYF 335
            ||:||.|||.|..|.. :||||:|.|||:||.|......:..|...|.|:|.:|||||.:::.:|
Mouse   228 IDIINLDTFNYIESASELRGGFDWSLHFQWEQLSLEQKALRLDPTEPIRTPIIAGGLFVIDKAWF 292

  Fly   336 QHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDG-ANTMLKNSLR 399
            .:||:||:.||||||||.|||||.|.|||.::|:|||||||:|||:.||..||| |||.:||:.|
Mouse   293 DYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHVFRKKHPYVFPDGNANTYIKNTKR 357

  Fly   400 LAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGE------ 458
            .|.||||:||.||...........:|:|.:||.||:.|.|:.|.|||:||||||.||.:
Mouse   358 TAEVWMDEYKQYYYAARPFALERPFGNIENRLNLRKNLHCQTFKWYLENVYPELRVPPDSSIQKG 422

  Fly   459 ---------ESKKSAAAPIFQ--PW------HSRKRNYVDTFQLRLTGTELCAAVV-----APKV 501
                     ||:|.....|.:  |.      .::.:.:..|:..::...|||.:||     ||.|
Mouse   423 NIRQRQKCLESQKQKKQEILRLSPCAKVKGDGAKSQVWAFTYTQQIIQEELCLSVVTLFPGAPVV 487

  Fly   502 KGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEAS--GDA-----QVTVNKCHEMLGD 559
            ....|.|..          .|||.:|......:...|||:..  ||:     :|.||.|...|..
Mouse   488 LALCKNGDE----------RQLWTKTGARIEHIASHLCLDTDMFGDSTEDGKEVVVNPCESSLMS 542

  Fly   560 QQW 562
            |.|
Mouse   543 QHW 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	150/300 (50%)
		RICIN	489..610	CDD:214672	26/86 (30%)
		RICIN	490..609	CDD:238092	26/85 (31%)
Galnt14	NP_082140.2	Catalytic subdomain A	110..215		54/111 (49%)
		Glyco_tranf_2_3	111..337	CDD:290369	116/232 (50%)
		pp-GalNAc-T	114..408	CDD:133004	150/300 (50%)
		Catalytic subdomain B	274..336		38/61 (62%)
		RICIN	422..547	CDD:238092	32/134 (24%)
		Ricin_B_lectin	422..545	CDD:279046	31/132 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820