Protein Alignment Pgant35A and GALNT17

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_071924.1
• Gene: GALNT17 / 64409
• HGNCID: 16347
• Length: 598
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 180/563 - (31%)
• Similarity: 262/563 - (46%)
• Gaps: 94/563 - (16%)

  Fly    75 GESPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQ 139
            |..||...|..:.:       .:...:||    ||     |:.:|..|.|.|:|||.|...|  :
Human    97 GGLPATLSPAEEEK-------AKGPHEKY----GY-----NSYLSEKISLDRSIPDYRPTKC--K 143

  Fly   140 ETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLR 204
            |...:::|||.||:..|.||....::||:.:.:..||::||:|||||||:||..||:..|...:.
Human   144 ELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVH 208

  Fly   205 ARLKYDNL-RYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLA 268
            .|  |..| :.::|::||||||:|:.|.:.|.|.|..|.|:|:|....|.||:|..|:.....:.
Human   209 KR--YPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVI 271

  Fly   269 VPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRG------PFRSPTMAGGL 327
            :|.||.|..|.||.........|::|.|...:       :..|:|:..      |.|:|.|.|..
Human   272 LPSIDNIKQDNFEVQRYENSAHGYSWELWCMY-------ISPPKDWWDAGDPSLPIRTPAMIGCS 329

  Fly   328 FAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANT 392
            |.||||:|..:|..|..||::||||||:..:.|.|||:::::|||||.||.||::||.|..|..|
Human   330 FVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYT 394

  Fly   393 MLKNSLRLAHVWMDQYKDYYLKHEKVP---KTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELH 454
            . :|:||:|.||||.||.:......:|   ...|.||:|:|..||:.|:|::|.|||.:||||:.
Human   395 K-RNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQWYLDHVYPEMR 458

  Fly   455 VPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRT 519
                                |..|.|...:||..           |.|........|:..|....
Human   459 --------------------RYNNTVAYGELRNN-----------KAKDVCLDQGPLENHTAILY 492

  Fly   520 PNQLWYETEKAEIVLDKLLCLEASG------DAQVTVNKCHEMLGD------------QQWRHTR 566
            |...| ..:.|....:..|.|.|.|      |.:..|:.....|..            ::|...:
Human   493 PCHGW-GPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQ 556

  Fly   567 NANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNGAGGSWDI 609
              |..:.|...|.||..   ....|..:||..:| ..|..|.|
Human   557 --NGAIMNKGTGRCLEV---ENRGLAGIDLILRS-CTGQRWTI 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	122/308 (40%)
		RICIN	489..610	CDD:214672	27/139 (19%)
		RICIN	490..609	CDD:238092	26/136 (19%)
GALNT17	NP_071924.1	Catalytic subdomain A	151..262		49/112 (44%)
		pp-GalNAc-T	155..454	CDD:133004	122/308 (40%)
		Catalytic subdomain B	319..381		32/61 (52%)
		RICIN	467..593	CDD:238092	28/143 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810