DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and galnt1

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_031759269.1	Gene:	galnt1 / 594943	XenbaseID:	XB-GENE-1013398	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	550	Identity:	214/550 - (38%)
Similarity:	305/550 - (55%)	Gaps:	75/550 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GESP-AAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDR 138
            |:.| ...||...|.::....|:..::.:.:::: :|.:.||.:.|..|.|.|::||.|.:.|
Frog    45 GDGPDINQKPHEGPGEMGKPVVIPKEEQEKMKEM-FKINQFNLMASEMIALNRSLPDVRLEGC-- 106

  Fly   139 QETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDL 203
            :.....::||..|:|:.|:||...||:|::.:|:.|:|.:||:|||||||.|   |.||
Frog   107 KTKVYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDAS---EREF------ 162

  Fly   204 RARLKYDNLRYIKN----------EQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLR 258
               ||.....|:|.          |||.||||:|:.||..:.|.|:.|||:|.|....||||||.
Frog   163 ---LKRPLETYVKKLTVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLA 224

  Fly   259 LIKSENATLAVPVIDLINADTFEY-TPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRG----PF 318
            .||.:..|:..|:||:|:.||||| ..|.:..|||||.|:|||..:|:..:   :..||    |.
Frog   225 RIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREM---DRRRGDRTLPV 286

  Fly   319 RSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRP 383
            |:||||||||:::|.|||.:|.||..||||||||:|||||.|||||.::||.||.|||:|||..|
Frog   287 RTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATP 351

  Fly   384 YTSPDGANTML-KNSLRLAHVWMDQYKD-YYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYL 446
            ||.|.|...:: ||:.|||.||||::|: :|:....|.|. ||||||.|:.||.:|||:.|:|||
Frog   352 YTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKV-DYGDISTRVGLRHKLQCKPFSWYL 415

  Fly   447 KNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSL 511
            :||||:..:|                    |:|....::|...|..|...:|.      |:...:
Frog   416 ENVYPDSQIP--------------------RHYYSLGEIRNVETNQCLDNMAR------KENEKV 454

  Fly   512 QLQTCR-RTPNQLWYETEKAEIVLDKLLCLEASG-DAQVTVNKCHEMLGDQQWRHTRNANSPV-- 572
            .:..|. ...||::..|...||..|. |||:.|. :..|.:.|||.:.|:|.|.:     .||
Frog   455 GIFNCHGMGGNQVFSYTASKEIRTDD-LCLDVSKLNGPVIMLKCHHLRGNQLWEY-----DPVKL 513

  Fly   573 --YNMAKGTCLRAAAPTTGALISLDLCSKS 600
              .::....||..||.....:.|:..||.|
Frog   514 TLVHVNSNQCLDKAAEEDSQVPSIRDCSGS 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	156/315 (50%)
		RICIN	489..610	CDD:214672	31/117 (26%)
		RICIN	490..609	CDD:238092	31/116 (27%)
galnt1	XP_031759269.1	pp-GalNAc-T	119..419	CDD:133004	156/315 (50%)
galnt1	XP_031759269.1	Ricin_B_lectin	432..548	CDD:395527	32/123 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010