DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant35A and galnt8a.1

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_021326338.1	Gene:	galnt8a.1 / 568547	ZFINID:	ZDB-GENE-091015-4	Length:	597	Species:	Danio rerio

Alignment Length:	681	Identity:	184/681 - (27%)
Similarity:	306/681 - (44%)	Gaps:	183/681 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGTLLV-AVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAE-----------------LSYQA 60
            :|.|:: .:::.|..:|:....:|          :||...|||                 |:.:.
Zfish     7 VGVLVIGCILYSLVYMFFIRPEQS----------KGNRLQRAEDLDVLQRLKRIEDQVHHLALEV 61

  Fly    61 RVTVGCTPNASITTGESPAAPK----------PPSDP------------EQLELLGVVRNKQDKY 103
            |         |....|:|...|          .|:.|            ||:|        .:|.
Zfish    62 R---------SQKVKEAPVGQKITKKTEVKKLYPNSPLFSSWGAELTEEEQME--------AEKL 109

  Fly   104 IRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSI 168
            .::.||     |..:||.:.|.|.|||||...|..:  ...::||..|:::.:.||....:.|::
Zfish   110 FQEFGY-----NVFLSNRLPLNRTIPDTRDPRCALK--IYPKDLPTISVILIYLNEALSVIKRAV 167

  Fly   169 KTVLERTPSYLLREIILVDDHSDLPELEFHLHG--DLRARLKYDNLRYIKNEQREGLIRSRVIGA 231
            .:::::||::||:||:||||:|...:|:..|:.  ||..:.|...::.::::::.||.::|:.|.
Zfish   168 HSIIDKTPAHLLKEIVLVDDNSSNEDLQLPLNKYIDLINKAKPGLIKKVRHKRQMGLAKARMSGW 232

  Fly   232 REAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFE---YTPSPLVRGGFN 293
            ..|.|.|:..||:||||:::|.||||..||:...|:..||.|.:..||.|   |.|:   ...|:
Zfish   233 EAATGQVVAILDAHIEVHKEWAEPLLARIKANRTTVLSPVFDKVLFDTLEVINYNPA---AHAFD 294

  Fly   294 WGLHFRWENL-PEG-TLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEIS 356
            |.|...:|:. ||. .|..|.:   |.:||::.|.|.| :|::...:|..|..|.|:||||:|:.
Zfish   295 WSLWCMYESFRPEWYKLNDPSE---PGKSPSVMGILVA-DRQFLGEIGALDDGMTIYGGENVELG 355

  Fly   357 FRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYK-------DYYLK 414
            .|.|.|||::::||||::.||.|..:|| |||.:..|::|:||:|.:|||:||       :..||
Zfish   356 IRVWLCGGSVEVVPCSKIAHIERAHKPY-SPDLSKPMIRNALRVAEIWMDEYKSNVNIAWNLPLK 419

  Fly   415 HEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWH------ 473
            ...:    |.|::::|.:|||:|:|:.|.|||:||||:|                ..|.
Zfish   420 DHGI----DIGNVTERKQLREKLKCKPFKWYLENVYPQL----------------DRWDGIMAYG 464

  Fly   474 SRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLL 538
            :.|.:.::.|.:.....                .||...|..|.....|..:..:..||.:..:.
Zfish   465 TLKNDILENFCIDQGPV----------------PGSVPILYGCHYYEPQYCFYNQNGEIYIGGIK 513

  Fly   539 CLEASGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNGA 603
                                    .||.|:|         .||  ..|.:|:..:|..|..:...
Zfish   514 ------------------------SHTYNSN---------RCL--TDPGSGSTPALHNCKNAQEK 543

  Fly   604 GGS--WDIVQLKKPTEAEGRAKEARNSDKAL 632
            |.:  ||..|        |.|...|.:::.|
Zfish   544 GMNIYWDFTQ--------GNAIRNRKTNRCL 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	115/312 (37%)
		RICIN	489..610	CDD:214672	20/122 (16%)
		RICIN	490..609	CDD:238092	19/120 (16%)
galnt8a.1	XP_021326338.1	pp-GalNAc-T	150..451	CDD:133004	115/312 (37%)
galnt8a.1	XP_021326338.1	RICIN	464..590	CDD:238092	27/162 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910