DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and galnt8a.2

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_021326339.1	Gene:	galnt8a.2 / 568500	ZFINID:	ZDB-GENE-131122-40	Length:	609	Species:	Danio rerio

Alignment Length:	569	Identity:	170/569 - (29%)
Similarity:	275/569 - (48%)	Gaps:	134/569 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 SDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQ 149
            ::.||:|        .:|..::.||     |..:||.:.|.|.|||||...|..:  ...::||.
Zfish   100 TEEEQME--------AEKLFQEFGY-----NVFLSNRLPLNRTIPDTRDPRCSLK--IYPKDLPT 149

  Fly   150 ASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHL--HGDLRARLKYDNL 212
            .|:::.:.||....:.|::::::::||::||:||:||||:|...:|:..|  :.||..:.|...:
Zfish   150 ISVILIYLNEALSVIKRAVQSIIDKTPAHLLKEIVLVDDNSSNEDLKLPLDKYIDLINKGKPGLI 214

  Fly   213 RYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINA 277
            :.::::::.||.::|:.|...|.|.|:..||:||||:::|.||||..||:...|:..||.|.:..
Zfish   215 KKVRHKKQMGLAKARMSGWEAATGQVVAILDAHIEVHKEWAEPLLAQIKANRTTVLSPVFDKVLF 279

  Fly   278 DTFE---YTPSPLVRGGFNWGLHFRWENL-PEG-TLKVPEDFRGPFRSPTMAGGLFAVNRKYFQH 337
            ||.|   |.|:   ...|:|.|...:|.. ||. .||.|.:   |.:||::.|.|.| :|::...
Zfish   280 DTLEVIKYNPA---AHAFDWSLWCMYERFRPEWYKLKDPSE---PGKSPSVMGILVA-DREFLGE 337

  Fly   338 LGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAH 402
            :|..|..|.|:||||:|:..|.|.|||::::||||::.|:.|..:|| |||.:..|::|:||:|.
Zfish   338 IGVLDEGMTIYGGENVELGIRVWLCGGSVEVVPCSKIAHVERAHKPY-SPDLSKLMIRNALRVAE 401

  Fly   403 VWMDQYK-------DYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEES 460
            :|||:||       :..||...:    |.|::::|.:|||:|:|:.|.|||:||||.|.
Zfish   402 IWMDEYKSNVNIAWNLPLKDHGI----DIGNVTERKQLREKLKCKPFKWYLENVYPLLD------ 456

  Fly   461 KKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWY 525
                                                                     |..:.|.|
Zfish   457 ---------------------------------------------------------RWDDILGY 464

  Fly   526 ETEKAEIVLDKLLCLE---ASGDAQVTVNKCHEMLGDQQWRHTR-------NANSPVYNMAKGTC 580
            ...|.:|:  |..|::   ..|...|... || ..|.|:..:.|       :..|..||  ...|
Zfish   465 GVLKNDIL--KTHCIDQGPVPGSVPVLFG-CH-YYGPQRCYYKRTGEIYVGSIKSHTYN--SNRC 523

  Fly   581 LRAAAPTTGALISLDLC--SKSNGAGGSWDIVQLKKPTEAEGRAKEARN 627
            |  ..|.:|:.::|..|  :|..|....||..|          .||.||
Zfish   524 L--TDPGSGSTVTLYNCKYAKEKGFSIYWDFTQ----------GKEIRN 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	115/312 (37%)
		RICIN	489..610	CDD:214672	27/132 (20%)
		RICIN	490..609	CDD:238092	26/130 (20%)
galnt8a.2	XP_021326339.1	pp-GalNAc-T	151..452	CDD:133004	115/312 (37%)
galnt8a.2	XP_021326339.1	RICIN	475..591	CDD:238092	26/102 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810