DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and Galnt12

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_232988.6	Gene:	Galnt12 / 313233	RGDID:	1562001	Length:	576	Species:	Rattus norvegicus

Alignment Length:	464	Identity:	185/464 - (39%)
Similarity:	269/464 - (57%)	Gaps:	46/464 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RLLCKSC--GLGTLLVAVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTP 68
            |.:.:.|  ||.....|::.||||......||:..||.                     ||...|
  Rat     4 RAVRRRCPRGLRRGREALLALLALAGLGAVLRARSRSG---------------------TVDPVP 47

  Fly    69 NASITTG-ESPAAPKPPSDPEQLELLG-VVR---NKQDKYIRDIGYKHHAFNALVSNNIGLFRAI 128
            ..:...| ..|..|:||...:.|...| .||   ..::..:::...:.|..|..:|:.|.|.|.:
  Rat    48 TRTPHPGRHEPVLPRPPLPADALGAKGEAVRLQLQGEELRLQEESVQRHQINIYLSDRISLHRRL 112

  Fly   129 PDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLP 193
            |:..:.:| |:...:.:|||:.|:|:.||||...||:|::.:|||.:|..||.|:|||||:||..
  Rat   113 PERWNPLC-REVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDRE 176

  Fly   194 ELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLR 258
            .|:..|..:|.   :...:|.|:..:||||:|:|::||..|.|:||.|||.|.|.::.||||||:
  Rat   177 HLKEPLANELS---QLPKVRLIRASKREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQ 238

  Fly   259 LIKSENATLAVPVIDLINADTFEY---TPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGP--- 317
            .|..:.:.:..||||:|:.:||||   :..|.: |||:|.|.|.|..:|:...|:   .|.|
  Rat   239 RIHEKESAVVCPVIDVIDWNTFEYLGNSGEPQI-GGFDWRLVFTWHVVPQRERKL---MRSPIDV 299

  Fly   318 FRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRR 382
            .||||||||||||:::||::||.||..|::|||||:|.|||.|||||.::..|||.|||:|.|:.
  Rat   300 IRSPTMAGGLFAVSKRYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQA 364

  Fly   383 PYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLK 447
            ||:    .:..|.||:|.|.||||.:|:.|.......:...:||:::|.|||.:|||:||.|:|.
  Rat   365 PYS----RSKALANSVRAAEVWMDDFKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLD 425

  Fly   448 NVYPELHVP 456
            .||||||||
  Rat   426 TVYPELHVP 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	140/304 (46%)
		RICIN	489..610	CDD:214672
		RICIN	490..609	CDD:238092
Galnt12	XP_232988.6	pp-GalNAc-T	134..428	CDD:133004	140/304 (46%)
Galnt12	XP_232988.6	Ricin_B_lectin	440..569	CDD:395527
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920