Protein Alignment Pgant35A and Galnt13

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_036018146.1
• Gene: Galnt13 / 271786
• MGIID: 2139447
• Length: 613
• Species: Mus musculus
• Alignment Length: 673
• Identity: 225/673 - (33%)
• Similarity: 333/673 - (49%)
• Gaps: 142/673 - (21%)

  Fly     9 CKSCGLGTLLVAVVWLLA----LLFYS----------HSLRSSIRSAGWRIDEGNATPRAELSYQ 59
            ||.    .|..:::|:|.    ||::|          .||..::|:...|..||
Mouse     7 CKV----VLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAVISRNQEG----------- 56

  Fly    60 ARVTVGCTPNASITTGE-SPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIG 123
                          .|| ..|...|..|.|:::.|               :|.:.||.:.|:.|.
Mouse    57 --------------PGEMGKAVLIPKDDQEKMKEL---------------FKINQFNLMASDLIA 92

  Fly   124 LFRAIPDTRHK------VCDRQETTEAE----------------------------------NLP 148
            |.|::||.|.:      .|:..:|.:.|                                  .||
Mouse    93 LNRSLPDVRLEGQYCCGRCEELQTMQQERYARVYISTNFCSSILFWLKCNTELRCKTKVYPDELP 157

  Fly   149 QASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLR 213
            ..|:|:.|:||...||:|::.:|:.|:|.|||.|:|||||.|:...|:..|...::. |:.. ::
Mouse   158 NTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKT-LEVP-VK 220

  Fly   214 YIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINAD 278
            .|:.|:|.||||:|:.||..:.|.|:.|||:|.|....||||||..||.:..|:..|:||:|:.|
Mouse   221 IIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDD 285

  Fly   279 TFEY-TPSPLVRGGFNWGLHFRWENLPEGTL-KVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEY 341
            |||| ..|.:..|||||.|:|||..:|:..: :...|...|.|:||||||||:::|.||:.:|.|
Mouse   286 TFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTY 350

  Fly   342 DMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTML-KNSLRLAHVWM 405
            |..||||||||:|:|||.|||||:::||.||.|||:|||..|||.|.|...:: ||:.|||.|||
Mouse   351 DAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWM 415

  Fly   406 DQYKD-YYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIF 469
            |::|| :|:....|.|. ||||:|.|..|||.|:|:.|:|||:|:||:..:|
Mouse   416 DEFKDFFYIISPGVVKV-DYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIP------------- 466

  Fly   470 QPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCR-RTPNQLWYETEKAEIV 533
                   |.|....::|...|..|...:..      |:...:.:..|. ...||::..|...||.
Mouse   467 -------RRYYSLGEIRNVETNQCLDNMGR------KENEKVGIFNCHGMGGNQVFSYTADKEIR 518

  Fly   534 LDKLLCLEASG-DAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGAL-ISLDL 596
            .|. |||:.|. ...|.:.|||.|.|:|.|.:....::.|:.:.: :||.......|:. :|::.
Mouse   519 TDD-LCLDVSRLSGPVIMLKCHHMRGNQLWEYDAETHTLVHIITQ-SCLSMGKGEDGSQDLSMET 581

  Fly   597 CSKSNGAGGSWDIVQLKKPTEAE 619
            |:.|...  .|   .|:..|.||
Mouse   582 CNDSTFQ--KW---LLRNYTRAE 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	149/302 (49%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	32/133 (24%)
Galnt13	XP_036018146.1	pp-GalNAc-T	160..460	CDD:133004	149/302 (49%)
		beta-trefoil_Ricin-like	467..594	CDD:483949	34/139 (24%)