Protein Alignment Pgant35A and GALNT2

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_016856452.1
• Gene: GALNT2 / 2590
• HGNCID: 4124
• Length: 636
• Species: Homo sapiens
• Alignment Length: 657
• Identity: 224/657 - (34%)
• Similarity: 326/657 - (49%)
• Gaps: 157/657 - (23%)

  Fly     5 KRLLCKSCGLGTLLVAVVWLLALLFYSHSLRSSIRSAG----------WRIDEGNATPRAELSYQ 59
            :.|||         .|.:|:|.:.:|.:|...|..:.|          |  :|.:...:.:|.:
Human     6 RMLLC---------FAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDW--NEIDPIKKKDLHH- 58

  Fly    60 ARVTVGCTPNASITTGESPAAPK---PPS-----DPEQLELLG--VVRNKQDKYIRDIGYKHHAF 114
                         :.||..|...   ||.     |..|...:|  :||:.||.|.|      :.|
Human    59 -------------SNGEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYAR------NKF 104

  Fly   115 NALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYL 179
            |.:.|:.:.:.||||||||..|.|::.  ..:||..|:|:.|:||.:..|:|::.:||:::|.:|
Human   105 NQVESDKLRMDRAIPDTRHDQCQRKQW--RVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHL 167

  Fly   180 LREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDS 244
            ::|||||||:|:.||     .|.|..  |.:.:|.::|::||||:||||.||..|...||.||||
Human   168 IKEIILVDDYSNDPE-----DGALLG--KIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDS 225

  Fly   245 HIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYT-PSPLVRGGFNWGLHFRWENLPEGTL 308
            |.|.|:.||||||..:..:...:..|:||:||.|.|:|. .|..::|||:|.|.|:|:.:
Human   226 HCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYM----- 285

  Fly   309 KVPEDFR-------GPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAI 366
             .||..|       .|.::|.:|||||.:::.||:.||:|||.||:|||||:|||||.|||||::
Human   286 -TPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSL 349

  Fly   367 KIVPCSRVGHIFRKRRPYTSPDGANTML-KNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDR 430
            :|:|||||||:|||:.|||.|.|:.|:. :|:.|.|.||||:||::|.......:...||:|..|
Human   350 EIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSR 414

  Fly   431 LKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQ----------- 484
            |:||::|.|:.|.|||:||||||.||..:.....|.       .:..|.:||..
Human   415 LELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGAL-------QQGTNCLDTLGHFADGVVGVYE 472

  Fly   485 -LRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASGDAQV 548
             ....|.::||          |  ||.:   |||...::.|                   |...|
Human   473 CHNAGGNQVCA----------W--GSQV---TCRPRESRSW-------------------GGPDV 503

  Fly   549 TVNKCH--EMLGDQQWRHTRNANSPVYNMAKGTC----LRAAAPTTGAL-----------ISLDL 596
            ....||  ..:||            ||..|.|:|    |...||....:           :...|
Human   504 RSPSCHLSPGMGD------------VYEEAPGSCWPQPLWQPAPGPDRMSHTLVHQLCHQLRTRL 556

  Fly   597 CSKSNGA 603
            |....||
Human   557 CCSGKGA 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	143/307 (47%)
		RICIN	489..610	CDD:214672	28/132 (21%)
		RICIN	490..609	CDD:238092	27/131 (21%)
GALNT2	XP_016856452.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820