Protein Alignment Pgant35A and Galnt5

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_766443.2
• Gene: Galnt5 / 241391
• MGIID: 2179403
• Length: 930
• Species: Mus musculus
• Alignment Length: 586
• Identity: 193/586 - (32%)
• Similarity: 294/586 - (50%)
• Gaps: 98/586 - (16%)

  Fly    32 HSLRSSIR----SAGWRIDEGNATPRAELSYQARVTVGCTP---NASITTGESPAAPKPPSDPEQ 89
            |:.||::.    :.|::....|......:.:..|:.|..:|   ||....|.....|     ||:
Mouse   382 HTARSNLTAKAPTVGYQQSHANIPENPGMHHVFRIDVTLSPRDLNAPGQFGRPVVVP-----PEK 441

  Fly    90 LELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVM 154
                     |::...|   :|...||..:|:.|.:.|||.|||...|  .|.....:||..||:|
Mouse   442 ---------KKEAEQR---WKEGNFNVYLSDLIPVDRAIEDTRPAGC--AEQLVHNDLPTTSIIM 492

  Fly   155 CFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDL-RARLKYDNLRYIKNE 218
            ||.:|....|:||:.:||.|:|.:|::||:||||.|    .:.:|..|| :...::..:|.::.:
Mouse   493 CFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFS----TKEYLKADLDKYMSQFPKVRILRLK 553

  Fly   219 QREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEY- 282
            :|.||||:|:.||:.|.||||.|||||:|.|..||||||..:......:|.|||::||.....|
Mouse   554 ERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYM 618

  Fly   283 TPSPLVRGGFNWGLHFRWENLPEGTLK---VPE-DFRGPFRSPTMAGGLFAVNRKYFQHLGEYDM 343
            |.....||.|.|.::|.|:.:|...:.   :.| |.   .|.|.||||||::::.||..||.||.
Mouse   619 TVDNFQRGVFTWPMNFGWKTIPPDVVAKNGIKETDI---IRCPVMAGGLFSIDKSYFYELGTYDP 680

  Fly   344 AMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSP-DGANTMLKNSLRLAHVWMDQ 407
            .:|:|||||:|:||:.|.|||.|:|:||||||||||...||:.| |...|:.:|.:|:|.||:|.
Mouse   681 GLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDD 745

  Fly   408 YKDYYLKH--EKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPG------------- 457
            |::.:..|  ..:.:..|.|:::.:.:||::|:|:.|.|||.||:|:|..|.
Mouse   746 YRELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLDNVFPDLKAPVVRASGVLINMALG 810

  Fly   458 ------------EESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSS 510
                        |:...|:....|        ||  |:...:...|.|.|.:..|        .|
Mouse   811 KCVSIENITVTLEDCDGSSQLQQF--------NY--TWVRLIKHGEWCVAPIPEK--------GS 857

  Fly   511 LQLQTCRRTPNQL-WYETEKA----EIV-------LDKLLCLEAS-GDAQVTVNKCHEMLGDQQW 562
            |.|..|....|:| |.....:    |:|       ..:|||:|.: ....:.:..|:.|...|:|
Mouse   858 LTLYHCDNRNNRLKWLHKSASAFHPELVDHIVFENYQQLLCMEGNFSQKTLKLAACNPMELQQKW 922

  Fly   563 R 563
            :
Mouse   923 K 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	131/307 (43%)
		RICIN	489..610	CDD:214672	21/88 (24%)
		RICIN	490..609	CDD:238092	21/87 (24%)
Galnt5	NP_766443.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..209
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..381
		Catalytic subdomain A	485..594		53/112 (47%)
		pp-GalNAc-T	489..790	CDD:133004	131/307 (43%)
		Catalytic subdomain B	654..716		37/64 (58%)
		RICIN	805..925	CDD:214672	27/137 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810