Protein Alignment Pgant35A and Galnt18

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_776100.2
• Gene: Galnt18 / 233733
• MGIID: 2446239
• Length: 622
• Species: Mus musculus
• Alignment Length: 572
• Identity: 176/572 - (30%)
• Similarity: 274/572 - (47%)
• Gaps: 104/572 - (18%)

  Fly    76 ESPAAP-----KPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKV 135
            |:||.|     :|.:|.......|...:.:.:.:....::::.:||.:|:.:.|.|.:||.|...
Mouse    79 EAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSG 143

  Fly   136 CDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHL- 199
            |  :..:..::||:.|||..|.||....|:|||.:.:|||||:||:|||||||:|...||:..|
Mouse   144 C--RNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLT 206

  Fly   200 -HGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSE 263
             :.|.....|...::.:::.::||||||||.|.|.|...|:...|:|:|.|..|.||:|..||..
Mouse   207 EYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKEN 271

  Fly   264 NATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLF 328
            ...:..|..|.|..|.||....||...||:|.|..|:.|.|:...|: |:...|.|||.:. |.|
Mouse   272 RKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKL-ENSTAPIRSPALI-GCF 334

  Fly   329 AVNRKYFQHLGEYDMAMDIWGGENIEISFR---------------AWQCGGAIKIVPCSRVGHIF 378
            .|:|:||:.:|..|..|:::||||:|:..|               .|||||:::::||||:.||.
Mouse   335 IVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIE 399

  Fly   379 RKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKT---YDYGDISDRLKLRERLQCR 440
            |..:|||. |....:.:|:||:|.||||::|.:......:|:.   .|.|||:.|..||::|||:
Mouse   400 RAHKPYTE-DLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCK 463

  Fly   441 DFAWYLKNVYPELHVPG------------------EESKKSAAAPIFQPWHS---RKRNYVDTFQ 484
            .|.|||.:||||:.:..                  ::...:...||....|.   :...|..:.|
Mouse   464 TFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQ 528

  Fly   485 LR---LTGTE------------------LCAAVVAPKVKGFWK--KGSSLQLQTCRRTPNQLWYE 526
            :.   |:.|.                  .|:...|.::|..|:  :|.|:|.:..:|
Mouse   529 IHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKR-------- 585

  Fly   527 TEKAEIVLDKLLCLEASGDA------QVTVNKCHEMLGDQQWRHTRNANSPV 572
                        |||...::      |:.:.||    ..|.|..|....|.|
Mouse   586 ------------CLELQENSDMEFGFQLVLQKC----SGQHWTITNVLRSLV 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	128/318 (40%)
		RICIN	489..610	CDD:214672	20/110 (18%)
		RICIN	490..609	CDD:238092	20/109 (18%)
Galnt18	NP_776100.2	Catalytic subdomain A	153..267		52/113 (46%)
		pp-GalNAc-T	157..473	CDD:133004	128/318 (40%)
		Catalytic subdomain B	324..400		30/76 (39%)
		Ricin_B_lectin	484..611	CDD:279046	22/150 (15%)
		RICIN	486..613	CDD:238092	23/150 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810