Protein Alignment Pgant35A and Galnt11

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_659157.1
• Gene: Galnt11 / 231050
• MGIID: 2444392
• Length: 608
• Species: Mus musculus
• Alignment Length: 625
• Identity: 266/625 - (42%)
• Similarity: 363/625 - (58%)
• Gaps: 65/625 - (10%)

  Fly     6 RLLCKSCGLGTLLVAVVWLLALLFY------SHSLRS-SIRSAG----------WRIDEGNATPR 53
            |..|..|    |..:..|.:.|..|      :..||: .|:.:|          .|...|   |.
Mouse     7 RYFCYGC----LFTSATWTVLLFIYFNFSEVTQPLRNVPIKGSGPHGPFPKKFYPRFTRG---PG 64

  Fly    54 AELSYQARVT-VGCTPNASITTGESPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNAL 117
            ..|..|.:.. :....|..|   |.|......|..|    ||::.|::|:.:||:||:.||||.|
Mouse    65 RVLDPQFKANRIDRLMNNHI---EDPDKGLSKSSSE----LGMIFNERDQELRDLGYQKHAFNML 122

  Fly   118 VSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLRE 182
            :||.:|..|.:||||:..|.|:  :...:||.||||:|||||....|:|::.:|::|||::||.|
Mouse   123 ISNRLGYHRDVPDTRNAECRRK--SYPTDLPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHE 185

  Fly   183 IILVDDHSDLP----ELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLD 243
            ||||||.||..    ||:.::...|.|::|     .|:|.:||||||.|:|||..|.|:||||||
Mouse   186 IILVDDSSDFDDLKGELDEYIQRYLPAKVK-----VIRNMKREGLIRGRMIGAAHATGEVLVFLD 245

  Fly   244 SHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTL 308
            ||.|||..||:|||.:|..:..|:..||||:|:|||..|:.||:|||||||||||:|:.:|...|
Mouse   246 SHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSEL 310

  Fly   309 KVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSR 373
            ..|:....|.|||||||||||:||:||..||:||..||||||||:|||||.|.|||.:.|:||||
Mouse   311 GGPDGATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSR 375

  Fly   374 VGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQ 438
            |||||||||||.||:|.:||..|||||||||:|:||:.|.......|...:|:||:|::||::|.
Mouse   376 VGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKNKSFGNISERVELRKKLG 440

  Fly   439 CRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKG 503
            |:.|.|||.|:|||:.:||..:|..  .|:......::...:...:|....|..|  :||.....
Mouse   441 CQSFKWYLDNIYPEMQIPGPNAKPQ--QPVLINRGPKRPRVLQRGRLYHLQTNKC--LVAQGRSS 501

  Fly   504 FWKKGSSLQLQTC-RRTPNQLWYETEKAEIVLDKLLCLEAS---GDAQVTVNKCHEMLGDQQWRH 564
              :||..:.|:|| ...|.|:|...|..|::|:.||||:.|   ......:.|||...|.|||
Mouse   502 --QKGGLVLLKTCDYGDPTQVWIYNEDHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQW-- 562

  Fly   565 TRNANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNGAG 604
            |...|:.:|.::.|.|||.          :||..:....|
Mouse   563 TFGKNNRLYQVSVGQCLRV----------MDLMDQKGYVG 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	173/302 (57%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	38/131 (29%)
Galnt11	NP_659157.1	Catalytic subdomain A	150..261		63/115 (55%)
		pp-GalNAc-T	154..452	CDD:133004	173/302 (57%)
		Catalytic subdomain B	319..381		46/61 (75%)
		beta-trefoil_Ricin_GALNT11	478..604	CDD:467318	38/131 (29%)