Protein Alignment Pgant35A and Galnt17

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_660253.2
• Gene: Galnt17 / 212996
• MGIID: 2137594
• Length: 598
• Species: Mus musculus
• Alignment Length: 560
• Identity: 180/560 - (32%)
• Similarity: 262/560 - (46%)
• Gaps: 96/560 - (17%)

  Fly    84 PSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLP 148
            ||:.|:      .:...:||    ||     |:.:|..|.|.|:|||.|...|  :|...::.||
Mouse   105 PSEEEK------AKGPHEKY----GY-----NSYLSEKISLDRSIPDYRPTKC--KELKYSKELP 152

  Fly   149 QASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNL- 212
            |.||:..|.||....::||:.:.:..||::||:|||||||:||..||:..|...:..|  |..|
Mouse   153 QISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKR--YPGLV 215

  Fly   213 RYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINA 277
            :.::|::||||||:|:.|.:.|.|.|..|.|:|:|....|.||:|..|:.....:.:|.||.|..
Mouse   216 KVVRNQKREGLIRARIEGWKAATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQ 280

  Fly   278 DTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRG------PFRSPTMAGGLFAVNRKYFQ 336
            |.||.........|::|.|...:       :..|:|:..      |.|:|.|.|..|.||||:|.
Mouse   281 DNFEVQRYENSAHGYSWELWCMY-------ISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFG 338

  Fly   337 HLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLA 401
            .:|..|..||::||||||:..:.|.|||:::::|||||.||.||::||.|..|..|. :|:||:|
Mouse   339 EIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTK-RNALRVA 402

  Fly   402 HVWMDQYKDYYLKHEKVP---KTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKS 463
            .||||.||.:......:|   ...|.||:|:|..||:.|:|::|.|||.:||||:.
Mouse   403 EVWMDDYKSHVYIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMR--------- 458

  Fly   464 AAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETE 528
                       |..|.:...:||..           |.|........|:..|....|...| ..:
Mouse   459 -----------RYNNTIAYGELRNN-----------KAKDVCLDQGPLENHTAILYPCHGW-GPQ 500

  Fly   529 KAEIVLDKLLCLEASG------DAQVTVNKCHEMLGD------------QQWRHTRNANSPVYNM 575
            .|....:..|.|.|.|      |.:..|:.....|..            ::|...:  |..:.|.
Mouse   501 LARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQ--NGAIMNK 563

  Fly   576 AKGTCLRAAAPTTGALISLDLCSKSNGAGGSWDIVQLKKP 615
            ..|.||..   ....|..:||..:| ..|..|.|   |.|
Mouse   564 GTGRCLEV---ENRGLAGIDLILRS-CTGQRWAI---KNP 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	122/308 (40%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	29/148 (20%)
Galnt17	NP_660253.2	Catalytic subdomain A	151..262		49/112 (44%)
		pp-GalNAc-T	155..454	CDD:133004	122/308 (40%)
		Catalytic subdomain B	319..381		32/61 (52%)
		beta-trefoil_Ricin_GALNT17	457..598	CDD:467352	33/181 (18%)