Protein Alignment Pgant35A and gly-10

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001041036.2
• Gene: gly-10 / 178343
• WormBaseID: WBGene00001635
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 207/672 - (30%)
• Similarity: 317/672 - (47%)
• Gaps: 96/672 - (14%)

  Fly     2 MQIKRLLC-KSCGLGTLLVA----VVWLLALLFYSHSLRSSIRSA--------------GWRIDE 47
            |:..|::. :|.||...|..    |:....||.:.:.:.|.:.::              |...|.
 Worm    71 MKFPRVITFQSMGLSRYLSRRHHWVIQYCGLLLFLYLIYSYVATSNDGPNLHEDIPVFQGQGKDR 135

  Fly    48 GNATPRAEL---------SYQARVTVGCTPNASITTGESPAAP----KPPSDPEQLELLGVVRNK 99
            .|..|.|.|         .|:....:.....|:....:....|    ||...||..|:
 Worm   136 ANPNPPAALGDEALDPFEKYRGHEKIKWEDEAAYEKEKRREGPGEWGKPVKLPEDKEV------- 193

  Fly   100 QDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTL 164
             :|....: ||.:.:||.:|:.|.|.|:|.|.|||.|  :....:..||..|::..|:.||..||
 Worm   194 -EKEALSL-YKANGYNAYISDMISLNRSIKDIRHKEC--KNMMYSAKLPTVSVIFPFHEEHNSTL 254

  Fly   165 MRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNL-RYIKNEQREGLIRSRV 228
            :||:.:|:.|:|..||:|||||||.|:.|.|...|. |...:.|.|:: :.::.::||||||.|.
 Worm   255 LRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLE-DFLKKNKIDHIVKVLRTKKREGLIRGRQ 318

  Fly   229 IGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPL-VRGGF 292
            :||::|.|::|:|||:|.|.|..||.|||..|..:..|:..|.:|:|:.:|:|..|... .||.|
 Worm   319 LGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSF 383

  Fly   293 NWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISF 357
            :|.  |.::.||. |.|..|....||.||.||||.||::.|:|..||.||..:||||||..|:||
 Worm   384 DWA--FNYKRLPL-TKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSF 445

  Fly   358 RAWQCGGAIKIVPCSRVGHIFR-KRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKT 421
            :.|||.|.:...|||||.||:| |..|:.:....:.:.:|..|:|.||||.||:...||......
 Worm   446 KVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLYKHRPGVGN 510

  Fly   422 YDYGDISDRLKLRERLQCRDFAWYLKNVY--PELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQ 484
            .|.||:.....:||:|||:.|.|::|.:.  .:.:.|..|.|.||..                 :
 Worm   511 ADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAVEPKASAEG-----------------E 558

  Fly   485 LRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQ----------LWYE--TEKAEIVLDKL 537
            :|..||..|...      .|.::.....|:.|......          .|::  .:..:|..|
 Worm   559 IRNVGTNFCIDT------QFKEQNQRFGLRKCTSDDKDGGGEQDLRLTRWHDIRPKGRKICFD-- 615

  Fly   538 LCLEASGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNG 602
             |..:...|.|.:..||.|.|:|.::: |.|...:|:...|.||.|.....|.|......|.|:.
 Worm   616 -CSTSVDKAPVILFDCHSMKGNQLFKY-RVAQKQIYHPISGQCLTADENGKGFLHMKKCDSSSDL 678

  Fly   603 AGGSW-----DIVQLKKPTEAE 619
            ...:|     ::::.::..||:
 Worm   679 QKWAWQTVDNELLETRQANEAK 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	129/301 (43%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	30/147 (20%)
gly-10	NP_001041036.2	pp-GalNAc-T	241..539	CDD:133004	129/301 (43%)
		beta-trefoil_Ricin_GALNT10-like	555..683	CDD:467317	30/154 (19%)