Protein Alignment Pgant35A and gly-5

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001379253.1
• Gene: gly-5 / 176736
• WormBaseID: WBGene00001630
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 238/635 - (37%)
• Similarity: 332/635 - (52%)
• Gaps: 104/635 - (16%)

  Fly    17 LLVAVVWLLALLFYSHSLRSSIR-----SAGWRIDEGNATPRAELSYQARVTVGCTP-------- 68
            |||.|.|:.:|:|::.:...|.:     ....:|.|.|..|:|.   :..|..|..|
 Worm    14 LLVPVFWICSLIFFAATSNDSSQIGSNNDLANKIAEANFHPKAA---KQDVIQGFGPPIEPEPVV 75

  Fly    69 -NASITTGESP----AAPK---PPSDP-------EQLELLG--VVRNK-----QDKYIRDIGYKH 111
             |..:...|.|    |.||   .|:||       .|...||  ||.:|     ::|...|.|..:
 Worm    76 ENNKVEEEEQPGGNLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLN 140

  Fly   112 HAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTP 176
            :|||...|:.|.:.|.:|......|..::..  ||||:.|:::||:||....|:|::.:||||||
 Worm   141 NAFNQYASDMISVHRTLPTNIDAECKTEKYN--ENLPRTSVIICFHNEAWSVLLRTVHSVLERTP 203

  Fly   177 SYLLREIILVDDHSDLPELEFHLHGDLRARLKY--DNLRYIKNEQREGLIRSRVIGAREAVGDVL 239
            .:||.|::||||.||:.    |....|...:..  ..::.::.|:||||||:|:.||..|.|:||
 Worm   204 DHLLEEVVLVDDFSDMD----HTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVL 264

  Fly   240 VFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLV---RGGFNWGLHFRWE 301
            .:||||.|..:.|:||||..||.:..|:..||||:|:.:||||..|...   .|||:|||.|.|.
 Worm   265 TYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWH 329

  Fly   302 NLPEGTLK---VPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCG 363
            ::||...|   .|.|   |.||||||||||::::|||:.||.||...|||||||:|:||:.|.||
 Worm   330 SIPERDRKNRTRPID---PVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCG 391

  Fly   364 GAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTY-DYGDI 427
            |.::|||||.|||:||||.||....|.|.:.:||:|||.||:|.||.||  :|::.... |:|||
 Worm   392 GTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYY--YERINNQLGDFGDI 454

  Fly   428 SDRLKLRERLQCRDFAWYLKNVYPELHVPGE-----ESKKSAAAP-----IFQPWHSRKRNYVDT 482
            |.|.||||.|.|:.|.|||.|:||||.||||     |.:.||..|     .....|.:.|. |.|
 Worm   455 SSRKKLREDLGCKSFKWYLDNIYPELFVPGESVAKGEVRNSAVQPARCLDCMVGRHEKNRP-VGT 518

  Fly   483 FQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASGDAQ 547
            :|....|                              .||.|..::..||..|: .|::.:| :.
 Worm   519 YQCHGQG------------------------------GNQYWMLSKDGEIRRDE-SCVDYAG-SD 551

  Fly   548 VTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALISLDLC 597
            |.|..||.|.|:|:||:..:... :.:.....||  .....||.:.:..|
 Worm   552 VMVFPCHGMKGNQEWRYNHDTGR-LQHAVSQKCL--GMTKDGAKLEMVAC 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	152/307 (50%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	26/120 (22%)
gly-5	NP_001379253.1	pp-GalNAc-T	178..477	CDD:133004	152/307 (50%)
		beta-trefoil_Ricin_Pgant9-like	485..610	CDD:467340	33/150 (22%)