Protein Alignment Pgant35A and Galnt10

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_598950.2
• Gene: Galnt10 / 171212
• MGIID: 1890480
• Length: 603
• Species: Mus musculus
• Alignment Length: 544
• Identity: 191/544 - (35%)
• Similarity: 280/544 - (51%)
• Gaps: 91/544 - (16%)

  Fly    81 PKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAE 145
            |.|.:|.|::               |..|:.:.||..||:.|.|.|::||.||..|:.:  ...|
Mouse    95 PYPMTDAERV---------------DQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSK--LYLE 142

  Fly   146 NLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYD 210
            .||..||::.|:||...:|:|::.:||.|:|..|:.||:||||.||...|:..|. |..|  .:.
Mouse   143 TLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLE-DYMA--LFP 204

  Fly   211 NLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLI 275
            ::|.::.::||||||:|::||..|.|||:.|||||.|.|..||.|||..|.....|:..|:||:|
Mouse   205 SVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVI 269

  Fly   276 NADTFEY--TPSPLVRGGFNWGLHFRWENLPEGTLKV-PEDFRGPFRSPTMAGGLFAVNRKYFQH 337
            :.|.|.|  .....:||.|:|.::::...:|....|. |.|   ||.||.||||||||:||:|..
Mouse   270 DHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSD---PFESPVMAGGLFAVDRKWFWE 331

  Fly   338 LGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAH 402
            ||.||..::|||||..||||:.|.|||.::.:||||||||:||..||..|.|. ::.:|..|:|.
Mouse   332 LGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGV-SLARNLKRVAE 395

  Fly   403 VWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNV-------YPELHVPGEES 460
            ||||:|.:|..:.....:....||:..:.|||..|.|:.|.|::..:       ||.:..|
Mouse   396 VWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYPPVEPP---- 456

  Fly   461 KKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQ--- 522
               |||     |.          ::|..||.||.......:      ||.|:|:||.|...:
Mouse   457 ---AAA-----WG----------EIRNVGTGLCTDTKLGTL------GSPLRLETCIRGRGEAAW 497

  Fly   523 --------LWYE-TEKAEIVLDKLLCLEA-SGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAK 577
                    .|.| ....:....|..|.:| |..:.||:..||.|.|:|.|::.:  :..:|:...
Mouse   498 NSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRK--DKTLYHPVS 560

  Fly   578 GTCLRAAAPTTGALISLDLCSKSN 601
            |:|:.              ||:|:
Mouse   561 GSCMD--------------CSESD 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	131/308 (43%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	32/137 (23%)
Galnt10	NP_598950.2	Catalytic subdomain A	144..253		52/111 (47%)
		pp-GalNAc-T	148..443	CDD:133004	131/301 (44%)
		Catalytic subdomain B	311..373		40/61 (66%)
		Flexible loop. /evidence=ECO:0000250	373..384		5/10 (50%)
		beta-trefoil_Ricin_GALNT10	454..603	CDD:467354	37/161 (23%)