Protein Alignment Pgant35A and Galnt4

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_056552.1
• Gene: Galnt4 / 14426
• MGIID: 894692
• Length: 578
• Species: Mus musculus
• Alignment Length: 614
• Identity: 229/614 - (37%)
• Similarity: 317/614 - (51%)
• Gaps: 108/614 - (17%)

  Fly    10 KSCGLGTLLVAVVWLLALL--FYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTPNASI 72
            |||    ||:|::.|..:|  |...:|.:|..:.|.|    ...||.            .|:..
Mouse    10 KSC----LLLALLTLAYILVEFSVSTLYASPGAGGAR----ELGPRR------------LPDLD- 53

  Fly    73 TTGESPAAP---KPPSD---------PEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLF 125
            |..|..:.|   |||:|         ..:|:|......:|::.|     :.:|.|..:|:.|.|.
Mouse    54 TREEDLSQPLYIKPPADSHALGEWGRASKLQLNEGELKQQEELI-----ERYAINIYLSDRISLH 113

  Fly   126 RAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHS 190
            |.|.|.|...| :.:.....:||..|:::.||||...||:|:|.:|||.:|:.||:|||||||.|
Mouse   114 RHIEDKRMYEC-KAKKFHYRSLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLS 177

  Fly   191 DLPELEFHLHGDLRARL-KYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLE 254
            |    ..:|...|...: ..:.:|.|:..:||||:|:|:|||..|.||||.|||.|.|.|..|||
Mouse   178 D----RIYLKAQLETYISNLERVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNTGWLE 238

  Fly   255 PLLRLIKSENATLAVPVIDLINADTFEY---TPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFR- 315
            |||..|..:...:..||||.|:.:|||:   |..|:: |||:|.|.|:|.::|    |...|.|
Mouse   239 PLLERISRDETAIVCPVIDTIDWNTFEFYMQTGEPMI-GGFDWRLTFQWHSVP----KHERDRRT 298

  Fly   316 ---GPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHI 377
               .|.||||||||||||::||||:||.||..|::|||||:|:|||.|||||.::|.|||.|||:
Mouse   299 SRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHV 363

  Fly   378 FRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDF 442
            |.||.||..|:    .|:|:.|.|.||||:||:::.......:...|||:|:|..|||||:|:.|
Mouse   364 FPKRAPYARPN----FLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDLSERKLLRERLKCKSF 424

  Fly   443 AWYLKNVYPELHVPGEESKKSAA--------------APIFQP---------WHSRKRN----YV 480
            .||||||:..||||.:......|              ||...|         .|.:..|    |.
Mouse   425 DWYLKNVFSNLHVPEDRPGWHGAIRSMGISSECLDYNAPDNNPTGANLSLFGCHGQGGNQFFEYT 489

  Fly   481 DTFQLRLTG-TELCAAVVAPKVKGFWKKGSSLQLQTCRR----TP-NQLWYETEKAEIVLDKL-L 538
            ...::|... |||||.|  |:.|.:      :.:|.|.:    .| |.:|:..|...|..... |
Mouse   490 SNKEIRFNSVTELCAEV--PQQKDY------VGMQNCPKDGLPVPVNIIWHFKEDGTIFHPHTRL 546

  Fly   539 CLE----ASGDAQVTVNKCHEMLGDQQWR 563
            ||.    |.|...|.:..|..:..:|.||
Mouse   547 CLSAYRTAEGRPSVHMKTCDALDKNQLWR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	152/306 (50%)
		RICIN	489..610	CDD:214672	25/86 (29%)
		RICIN	490..609	CDD:238092	25/84 (30%)
Galnt4	NP_056552.1	WcaA	133..430	CDD:223539	152/309 (49%)
		Catalytic subdomain A	134..243		56/112 (50%)
		pp-GalNAc-T	138..432	CDD:133004	152/306 (50%)
		Catalytic subdomain B	303..365		43/61 (70%)
		RICIN	446..576	CDD:238092	33/138 (24%)
		Ricin_B_lectin	446..574	CDD:279046	31/135 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820