Protein Alignment Pgant35A and GALNT5

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_016858726.1
• Gene: GALNT5 / 11227
• HGNCID: 4127
• Length: 956
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 197/605 - (32%)
• Similarity: 297/605 - (49%)
• Gaps: 112/605 - (18%)

  Fly    53 RAELSYQA----RVTVGCTPNASITTGESPA---------------------------------- 79
            |:|:|..:    ||.:..| |.::|.|..||
Human   363 RSEMSSSSLAPHRVPLSQT-NHALTGGLEPAKINITAKAPSTEYNQSHIKALLPEDSGTHQVLRI 426

  Fly    80 ----APKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQE 140
                :|:.|..|.|.....||.:.::|. .:..:|...||..:|:.|.:.|||.|||...|  .|
Human   427 DVTLSPRDPKAPGQFGRPVVVPHGKEKE-AERRWKEGNFNVYLSDLIPVDRAIEDTRPAGC--AE 488

  Fly   141 TTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRA 205
            .....|||..|::|||.:|...||:||:.:|:.|:|.:|::||:||||.|....|:.:|.   :.
Human   489 QLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLD---KY 550

  Fly   206 RLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVP 270
            ..::..:|.::.::|.||||:|:.||:.|.||||.|||||:|.|..||||||..:......:|.|
Human   551 MSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACP 615

  Fly   271 VIDLINADTFEY-TPSPLVRGGFNWGLHFRWENLPEGTL---KVPEDFRGPFRSPTMAGGLFAVN 331
            ||::||.....| |.....||.|.|.::|.|..:|...:   ::.|  ....|.|.||||||:::
Human   616 VIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVIAKNRIKE--TDTIRCPVMAGGLFSID 678

  Fly   332 RKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSP-DGANTMLK 395
            :.||..||.||..:|:|||||:|:||:.|.|||.|:|:||||||||||...||:.| |...|:.:
Human   679 KSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVER 743

  Fly   396 NSLRLAHVWMDQYKDYYLKH--EKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVP-- 456
            |.:|:|.||:|:||:.:..|  ..:.:..|.|:::.:.:||::|:|:.|.|||:||:|:|..|
Human   744 NLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAPIV 808

  Fly   457 -----------GEESKKSAAAPIFQPWHSRKR----NYVDTFQLRLTGT-ELCAAVVAPK----- 500
                       |:.........|.:.....|.    ||.   .|||... |.|.|.:..|
Human   809 RASGVLINVALGKCISIENTTVILEDCDGSKELQQFNYT---WLRLIKCGEWCIAPIPDKGAVRL 870

  Fly   501 ------VKGF-WKKGSS-------LQLQTCRRTP-------NQLWYETEKAEIVLDKLLCLEASG 544
                  .||. |...|:       |....|...|       |.:.:|..:      :|||||.:.
Human   871 HPCDNRNKGLKWLHKSTSVFHPELLSNSACGSFPALLSLQVNHIVFENNQ------QLLCLEGNF 929

  Fly   545 DAQV-TVNKCHEMLGDQQWR 563
            ..:: .|..|..:...|:|:
Human   930 SQKILKVAACDPVKPYQKWK 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	129/305 (42%)
		RICIN	489..610	CDD:214672	22/103 (21%)
		RICIN	490..609	CDD:238092	22/102 (22%)
GALNT5	XP_016858726.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820