DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and Galnt8

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_038965005.1	Gene:	Galnt8 / 103690194	RGDID:	9174049	Length:	583	Species:	Rattus norvegicus

Alignment Length:	551	Identity:	108/551 - (19%)
Similarity:	163/551 - (29%)	Gaps:	256/551 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 RNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHK 161
            |..||.::      ....:..:||.:....:||||.:..|..         ||.|:||.|.:..|
  Rat    43 REAQDLFL------EFGCSVFLSNQMPYNGSIPDTHNARCTG---------PQCSLVMNFGSHAK 92

  Fly   162 MTLMRSIK--------------------------------------------------------T 170
            ..:.|.:.                                                        .
  Rat    93 ERVDRGLSYISSCIACTEEVLSWNANIREAQQLCSLPAMFLSFVSAYRIPCHAALCNLGPWEAPP 157

  Fly   171 VLER--------TPSYLLREIILVDD---HSDLPE------------------------------ 194
            ::||        ||..||: ||||||   |.:.||
  Rat   158 IIERRHHQHHQPTPPQLLK-IILVDDISSHGEDPEGRRRSFQYPKKKLSEIYDGDPRMSWGKALA 221

  Fly   195 --------------------------------LEFHLH-----------GDLR-ARLKYDNLRY- 214
                                            ....||           |:|: .:.:..|..|
  Rat   222 YAICTLSQRSGAACRTVASPTGQCRTVYNFCIASIFLHAGLCWGGVWLGGELKDEKFQVYNQNYP 286

  Fly   215 ------IKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQW--------------------- 252
                  |::.:|.||......|...|..||:..||:.::||..|
  Rat   287 ILLRCLIRHTKRRGLAHDPNTGLEAATADVVAILDAPVDVNIGWTQNKDYMDSVESHARERETPF 351

  Fly   253 --------------LEPLLRLIKSE-------NATLAV--------PVIDLINADTFEYTPSPLV 288
                          |...:|||::.       .||:.:        ||.|.||.||||.....|.
  Rat   352 GNMDNFLPSLSKNGLHMTVRLIRASLSAPAHCGATVGLTVLSSFRAPVSDDINFDTFELKKDALA 416

  Fly   289 RGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENI 353
            ..||.|.|.:.::..|...:.: .|...|.|||:.. |:.|.||.:.:.:|..|..|.:.||:|:
  Rat   417 ADGFVWKLWYHYDPSPRAWIDL-GDASVPIRSPSFV-GIVATNRIFLEEIGALDGGMLLCGGQNV 479

  Fly   354 EISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKV 418
            .:..|.       :..|.|.          :...:|..|   .:||   :|
  Rat   480 GLGLRG-------EYFPSSL----------WVKAEGDVT---KALR---IW-------------- 507

  Fly   419 PKTYDYGDISDRLKLRERLQCRDFAWYLKNV 449
               ..|...:.|.:|.|:|:|:.|.||||.|
  Rat   508 ---ESYSTFASRKELWEKLKCKTFDWYLKIV 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	96/497 (19%)
		RICIN	489..610	CDD:214672
		RICIN	490..609	CDD:238092
Galnt8	XP_038965005.1	Glyco_tranf_GTA_type	272..535	CDD:416254	71/304 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010