DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and galnt5

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_017953060.2	Gene:	galnt5 / 101733275	XenbaseID:	XB-GENE-950717	Length:	1073	Species:	Xenopus tropicalis

Alignment Length:	573	Identity:	204/573 - (35%)
Similarity:	299/573 - (52%)	Gaps:	71/573 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RID---EGNATPRAELSYQARVTVGCTPNASITTGESPAAPK--------------PPSDPEQLE 91
            |||   :||.|   ||:.:..|.....|..::.....||.|:              .|.||....
Frog   512 RIDNAAKGNIT---ELTEEEGVKDKLVPPGNVPKDHEPAKPRSNKMHKVVPIDRTMSPRDPNAPG 573

  Fly    92 LLG----VVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASI 152
            .||    |..:||.:  ....::...||..:|:.|.|.|||.|||.:.|..|  ...::||..||
Frog   574 QLGRPVAVPEDKQGE--AQSRWREGHFNVYLSDLIPLDRAIQDTRPEGCSNQ--LIHDDLPTTSI 634

  Fly   153 VMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKN 217
            ::||.:|...|||||:.:||.|:|.:|::|||||||.|....|:..|...::   |...:|.:..
Frog   635 IICFIDEVWSTLMRSVYSVLNRSPEHLIKEIILVDDFSTRDYLKEKLDTYVK---KLPKVRVLHL 696

  Fly   218 EQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEY 282
            .:|.||||:|:.||..|.|:||.|||||:|.|..||||||..::.....:|.|||::|:|....|
Frog   697 PERHGLIRARIAGANIATGEVLTFLDSHVECNVGWLEPLLEQVRINRRKVACPVIEVISALDLSY 761

  Fly   283 -TPSPLVRGGFNWGLHFRWE-NLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAM 345
             |.....||.|.|.|:|.|: .|||...:.......|.:.|.||||||::.:.||..||.||..:
Frog   762 MTVESFQRGVFTWPLNFGWKAMLPEVIQRDNITEMDPIKCPVMAGGLFSIEKNYFYELGTYDPGL 826

  Fly   346 DIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSP-DGANTMLKNSLRLAHVWMDQYK 409
            |:|||||:||||:.|.|||.|:|:||||||||||...||:.| |...|:.:|.:|:|.||:|.||
Frog   827 DVWGGENMEISFKIWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRIKTVERNLVRVAEVWLDDYK 891

  Fly   410 DYYLKHEKVPKTY--DYGDISDRLKLRERLQCRDFAWYLKNVYPELHVP---------GEESKKS 463
            :.:..|.:....|  :.||::::.:|||||||::|.||:|||:|::..|         ..:.:|.
Frog   892 EIFYGHGQHLLKYLPNIGDLTEQKQLRERLQCKNFNWYIKNVFPDMGTPLLRATGMLSNPKLRKC 956

  Fly   464 AAAP----IFQPWHSRKRN--YVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRT-PN 521
            .|..    :.:.....|::  :..|:...:...:.|...|        :...|..||.|..| .|
Frog   957 LAIENSTFVLESCEGNKKSQQFSYTWLRHIRQGDQCIVPV--------ENEDSASLQPCDYTIVN 1013

  Fly   522 QLW--------YETEKAEIVLDK--LLCLEASGDA-QVTVNKCHEMLGDQQWR 563
            |.|        :.:.|..|:||.  :.||||..:: .:...:|..:...|:||
Frog  1014 QRWLHKSQISFHSSLKDHIMLDSTFITCLEADPESGGLVARECSSLKHYQKWR 1066

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	139/303 (46%)
		RICIN	489..610	CDD:214672	22/87 (25%)
		RICIN	490..609	CDD:238092	22/86 (26%)
galnt5	XP_017953060.2	pp-GalNAc-T	633..934	CDD:133004	139/303 (46%)
galnt5	XP_017953060.2	Ricin_B_lectin	944..1065	CDD:395527	24/128 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010