Protein Alignment Pgant35A and POC1B-GALNT4

DIOPT Version :9

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 210/550 - (38%)
• Similarity: 286/550 - (52%)
• Gaps: 102/550 - (18%)

  Fly    78 PAAPKPPSD---------PEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRH 133
            |...|||:|         ..:|:|......:|::.|     :.:|.|..:|:.|.|.|.|.|.|.
Human    59 PLYKKPPADSRALGEWGKASKLQLNEDELKQQEELI-----ERYAINIYLSDRISLHRHIEDKRM 118

  Fly   134 KVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFH 198
            ..|..|: .....||..|:::.||||...||:|:|.:|||.:|:.||:|||||||.||...|:..
Human   119 YECKSQK-FNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQ 182

  Fly   199 LHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSE 263
            |...:.   ..|.:|.|:..:||||:|:|:|||..|.||||.|||.|.|.|..||||||..|..:
Human   183 LETYIS---NLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRD 244

  Fly   264 NATLAVPVIDLINADTFEY---TPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFR----GPFRSP 321
            ...:..||||.|:.:|||:   ...|:: |||:|.|.|:|.::|    |...|.|    .|.|||
Human   245 ETAVVCPVIDTIDWNTFEFYMQIGEPMI-GGFDWRLTFQWHSVP----KQERDRRISRIDPIRSP 304

  Fly   322 TMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTS 386
            |||||||||::||||:||.||..|::|||||:|:|||.|||||.::|.|||.|||:|.||.||..
Human   305 TMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYAR 369

  Fly   387 PDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYP 451
            |:    .|:|:.|.|.||||:||:::.......:...|||||:|..|||||:|:.|.||||||:|
Human   370 PN----FLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFP 430

  Fly   452 ELHVPGEESKKSAAAPIFQP-WHSRKRN------------------------------------- 478
            .||||.:           :| ||...|:
Human   431 NLHVPED-----------RPGWHGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGNQFFE 484

  Fly   479 YVDTFQLRLTG-TELCAAVVAPKVKGFWKKGSSLQLQTCRR-----TPNQLWYETEKAEIVLDKL 537
            |....::|... |||||.|  |:.|.:      :.:|.|.:     ..|.:|:..|...|.....
Human   485 YTSNKEIRFNSVTELCAEV--PEQKNY------VGMQNCPKDGFPVPANIIWHFKEDGTIFHPHS 541

  Fly   538 -LCLEA----SGDAQVTVNKCHEMLGDQQW 562
             |||.|    .|...|.:..|..:..:|.|
Human   542 GLCLSAYRTPEGRPDVQMRTCDALDKNQIW 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	153/305 (50%)
		RICIN	489..610	CDD:214672	22/84 (26%)
		RICIN	490..609	CDD:238092	22/82 (27%)
POC1B-GALNT4	NP_001186710.1	WcaA	131..427	CDD:223539	153/307 (50%)
		pp-GalNAc-T	135..429	CDD:133004	153/305 (50%)
		RICIN	443..573	CDD:238092	25/136 (18%)
		Ricin_B_lectin	443..571	CDD:279046	25/135 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810