DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant35A and galnt6.3

DIOPT Version :9

Sequence 1:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_004911960.1	Gene:	galnt6.3 / 100498043	XenbaseID:	XB-GENE-22063205	Length:	622	Species:	Xenopus tropicalis

Alignment Length:	568	Identity:	203/568 - (35%)
Similarity:	303/568 - (53%)	Gaps:	72/568 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 CTPNASITTGESPAAPKPPSDPEQLELLGVVRNK-----QDKYIRDIGYKHHAFNALVSNNIGLF 125
            |.|.........|...:||.||......|....|     ::...::.|:..|.|||..|:.|.|.
Frog    87 CLPGYYTPAELKPFMERPPQDPNSPGADGKGFKKDTWTEEETKEKEKGFDKHCFNAFASDRISLH 151

  Fly   126 RAI-PDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDH 189
            ||: ||||..||..|:.....:||..|:::.|:||...||:|::.:||..:|:.||:|||||||.
Frog   152 RALGPDTRPPVCIEQKFKRCPSLPTTSVIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDA 216

  Fly   190 SDLPELEFHLHGDLRARLKYDNLRYIK---NEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQ 251
            |:...|:..|...::|      |:.:|   .::|:|||.:|::||..|.|:||.|||:|.|....
Frog   217 SEDEYLKEKLDDYVKA------LQIVKIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHG 275

  Fly   252 WLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPL------VRGGFNWGLHFRWENLPEGTLKV 310
            ||||||..|..::..:..|.|..|:.::||:. .|:      .||.|:|.|.|.||.:|....:.
Frog   276 WLEPLLSRIAEDHTAVVSPDITTIDLNSFEFA-KPVQYGKTHSRGNFDWSLTFGWEAIPAAEKER 339

  Fly   311 PEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVG 375
            .:|...|.:|||.|||||::::.||:|:|.||..|:||||||:|:|||.|||||.::|:|||.||
Frog   340 RKDETYPIKSPTFAGGLFSISKAYFEHIGSYDEEMEIWGGENVEMSFRVWQCGGQLEIIPCSVVG 404

  Fly   376 HIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYK-DYYLKHE---KVPKTYDYGDISDRLKLRER 436
            |:||.:.|:|.|.|...:.:|.:|||.||||.|| .||.::|   |:.:...:||||.||||:..
Frog   405 HVFRTKSPHTFPKGTQVISRNQVRLAEVWMDDYKLIYYRRNEQAAKMVREKSFGDISKRLKLKAD 469

  Fly   437 LQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKV 501
            |||::|.|||:|:|||:.||..:.....|                   ::..|::.|.. |....
Frog   470 LQCKNFTWYLENIYPEMFVPDRDPTYYGA-------------------VKNEGSQNCLD-VGENN 514

  Fly   502 KGFWKKGSSLQLQTCR-RTPNQLW-YETEKAEI--VLDKLLCLEAS-GDAQVTVNKCH------E 555
            .|    |..|.:..|. ...||.: |.|.| |:  .:.|.|||.:. |...|.:.:|.      .
Frog   515 HG----GKPLIMYPCHGMGGNQYFEYSTHK-ELRHNIAKQLCLRSKYGPGPVELGECQYKGKKTT 574

  Fly   556 MLGDQQWRHTRNANSPVYNMAKGTCL--RAAAPTTGALISLDLCSKSN 601
            :.|:::|..|:  :..:.|:....||  |...|:|..      |:.|:
Frog   575 VPGNEEWELTK--DRLLKNVGSNMCLTARGENPSTAE------CNPSD 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	138/311 (44%)
		RICIN	489..610	CDD:214672	31/126 (25%)
		RICIN	490..609	CDD:238092	30/125 (24%)
galnt6.3	XP_004911960.1	pp-GalNAc-T	178..483	CDD:133004	138/311 (44%)
galnt6.3	XP_004911960.1	Ricin_B_lectin	496..619	CDD:366226	32/152 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010