Protein Alignment Pgant35A and galnt6.2

DIOPT Version :10

• Sequence 1: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_031753046.1
• Gene: galnt6.2 / 100486937
• XenbaseID: XB-GENE-1000674
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 558
• Identity: 206/558 - (36%)
• Similarity: 295/558 - (52%)
• Gaps: 85/558 - (15%)

  Fly    66 CTPNASITTGESPAAPKPPSDPEQ--LELLGVVRN---KQDKYIRDIGYKHHAFNALVSNNIGLF 125
            |.|.........|...:||.||..  .:..|.::|   :::...::.|:..|.|||..|:.|.|.
 Frog    87 CLPGYYTPAELKPFMERPPQDPNSPGADGKGFIKNIWTEEEVEEKEKGFDKHCFNAFASDRISLH 151

  Fly   126 RAI-PDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDH 189
            ||: ||||...|..|:.....:||..||::.|:||...||:|::.:||..:|:.||:|||||||.
 Frog   152 RALGPDTRPLECIEQKFKRCPSLPTTSIIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDA 216

  Fly   190 SDLPELEFHLHGDLRARLKYDNLRYIK---NEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQ 251
            |:...|:..|...::|      |:.:|   .::|:|||.:|::||..|.|:||.|||:|.|....
 Frog   217 SEDEYLKEKLDDYVKA------LQIVKIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHG 275

  Fly   252 WLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPL------VRGGFNWGLHFRWENLPEGTLKV 310
            ||||||..:..::..:..|.|..||.:|||: ..|:      .||.|:|.|.|.||.:|....|.
 Frog   276 WLEPLLSRVAEDHTAVVSPDITAINYNTFEF-GKPVQQGKMNSRGNFDWSLAFNWEAIPAADEKQ 339

  Fly   311 PEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVG 375
            .:|...|.::||.|||||::::.||:|:|.||..|:||||||:|:|||.|||||.::|:|||.||
 Frog   340 RKDETYPIKTPTFAGGLFSISKAYFEHIGSYDEEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVG 404

  Fly   376 HIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKD-YYLKHE---KVPKTYDYGDISDRLKLRER 436
            |:||.:.|:|.|.|...:|:|.:|||.||||.||. ||.::|   |:.|...:||||.||||:..
 Frog   405 HVFRTKSPHTFPKGTQVILRNQVRLAEVWMDDYKVLYYRRNEQAAKIAKEKSFGDISKRLKLKAD 469

  Fly   437 LQCRDFAWYLKNVYPELHVP---------------------GEESKKSAAAPIFQPWHSRKRN-- 478
            |||::|.|||:|:|||:.||                     ||.:...:..||..|.|....|
 Frog   470 LQCKNFTWYLENIYPEMFVPDRDPTYYGAIKNEGTQNCIDVGENNNYGSQLPIMYPCHGMGGNQY 534

  Fly   479 --YVDTFQLRLT-GTELC---------AAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAE 531
              |....:||.. .|:||         ..:|..:.||          |......|:.|      |
 Frog   535 FEYSTHKELRHNLKTQLCLCSKYEPGPVKLVDCQYKG----------QNTTVPGNEEW------E 583

  Fly   532 IVLDKL-------LCLEASGDAQVTVNKCHEMLGDQQW 562
            ...|:|       :||.|.||...|. :|:....||.|
 Frog   584 FTKDRLIRNVGSNMCLTAQGDHPSTA-ECNPDDIDQLW 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	142/311 (46%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	26/106 (25%)
galnt6.2	XP_031753046.1	pp-GalNAc-T	178..483	CDD:133004	142/311 (46%)
		beta-trefoil_Ricin-like	493..623	CDD:483949	32/145 (22%)