DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and SCARF2

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_699165.3	Gene:	SCARF2 / 91179	HGNCID:	19869	Length:	871	Species:	Homo sapiens

Alignment Length:	196	Identity:	49/196 - (25%)
Similarity:	64/196 - (32%)	Gaps:	55/196 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 AKTRMAGAGPPNASHPIDL---------DSYVVYEERVRWDNI------QV--CCPGYR----TI 88
            |:.|.|| |||:...|..|         |:....|...|..|:      ||  ||.|:|    ..
Human    12 ARRRGAG-GPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQQGDEC 75

  Fly    89 LFGFCEPVCQEACPAHSYCAEPDRCHCQRGYEPSHHHTTGHQLICRPVCQGGCPEHSH------- 146
            ....||.  ...|..:..|..|..|.|:.||..::..|...:....|.|:..|..|.|
Human    76 GIAVCEG--NSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT 138

  Fly   147 --CVAH---------NECECWPGFKDASSWFSLSLRCE----------RVQCGHEQRFDPGRRAC 190
              |..|         :.|:|..|.....|.   :.|||          ...|....|.||...||
Human   139 GQCTCHARRWGARCEHACQCQHGTCHPRSG---ACRCEPGWWGAQCASACYCSATSRCDPQTGAC 200

  Fly   191 V 191
            :
Human   201 L 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	31/139 (22%)
SCARF2	NP_699165.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		4/8 (50%)
		PHA03247	<534..871	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	570..871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900