DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and Egfem1

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_006535622.1	Gene:	Egfem1 / 75740	MGIID:	1922990	Length:	658	Species:	Mus musculus

Alignment Length:	228	Identity:	50/228 - (21%)
Similarity:	65/228 - (28%)	Gaps:	97/228 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 CCPGY------RTILFGFCEPV--------CQEACPAHSYCAEPDRCHCQRGYEPSHHHTTGHQL 131
            |..||      ||.:..|....        |...|...:..|   ||.|..||:.|..
Mouse   253 CDTGYRRHADERTCIISFLSETDPCAGANGCAHLCQTENGMA---RCACHAGYQLSED------- 307

  Fly   132 ICRPVCQ--GGCPEH-----SHCVAHN---ECECWPGFK---DASSWFSLSLR----CER----- 174
              :..|:  ..|.|.     .|||...   .|.|.|||:   |....:.:.|.    ||:
Mouse   308 --KKACEDINECAEELAPCAHHCVNSKGSFTCTCHPGFELGADRKHCYRIELEIVNICEKNNGGC 370

  Fly   175 ------------VQCGHEQRFD-------------PGRRACVQI--------EMSMEELMQRVA- 205
                        ..|.|..:.|             .|...|.|:        |.|.||..|..:
Mouse   371 SHHCEPAIGGAHCSCNHGHQLDTDGKTCIDFDECESGEACCAQLCINYLGGYECSCEEGFQISSD 435

  Fly   206 ----ERLAKGLEAEEE-----------AANEPE 223
                :.|.:.||.|||           |.|.|:
Mouse   436 GCGCDALDEQLEEEEEEIDILRFPGRLAQNPPQ 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	40/200 (20%)
Egfem1	XP_006535622.1	EMI	71..140	CDD:369419
		FXa_inhibition	190..225	CDD:373209
		vWFA	<213..265	CDD:381780	3/11 (27%)
		vWFA	<268..310	CDD:381780	10/53 (19%)
		vWFA	<308..350	CDD:381780	12/41 (29%)
		FXa_inhibition	363..398	CDD:373209	5/34 (15%)
		vWFA	<395..436	CDD:381780	8/40 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900