DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and stab1

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001182543.1	Gene:	stab1 / 570626	ZFINID:	ZDB-GENE-050208-554	Length:	2553	Species:	Danio rerio

Alignment Length:	170	Identity:	50/170 - (29%)
Similarity:	66/170 - (38%)	Gaps:	55/170 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 CCPGYRTILFG-FCEPVCQE-ACPAHSYCAEPD---RCHCQRGYEPSHHHTTGHQLICRPV--CQ 138
            |.||.:   || .|..||.| .|..::.|...|   .|.|:.|:|....|       |.|:  |:
Zfish   210 CLPGNK---FGQACLDVCPEGTCGINAKCLSKDDKYNCECKEGFEGDGKH-------CIPINPCK 264

  Fly   139 ---GGCPEHSHCV-----AHNECECWPGFKD--------------ASSWFSLSLRCE-------R 174
               |.||..|...     ..::|.|.||.:.              |||..: |.|||       |
Zfish   265 TNNGDCPVTSTTCELISPGKSKCVCLPGMESSDPSKGCTQKSACTASSCHT-SARCETNGDGSPR 328

  Fly   175 VQCGHEQRFDPGRRACVQIEMSMEELMQRVAERLAKGLEA 214
            .:||.:|..| |||.       ...||:||.|...:|.:|
Zfish   329 CRCGSQQIGD-GRRC-------YGNLMERVVELDREGSQA 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	45/162 (28%)
stab1	NP_001182543.1	EGF_3	227..257	CDD:289699	8/36 (22%)
		Fasciclin	379..475	CDD:295423
		FAS1	455..630	CDD:225214
		Fasciclin	504..630	CDD:280607
		EGF_3	819..847	CDD:289699
		EGF_3	859..889	CDD:289699
		EGF_3	901..932	CDD:289699
		EGF_3	938..974	CDD:289699
		Fasciclin	1002..1103	CDD:280607
		Fasciclin	1125..1242	CDD:295423
		EGF_3	1458..1494	CDD:289699
		EGF_3	1500..1536	CDD:289699
		EGF_3	1542..1578	CDD:289699
		Fasciclin	1611..1711	CDD:280607
		Fasciclin	1734..1864	CDD:280607
		EGF_3	2085..2120	CDD:289699
		EGF_3	2128..2163	CDD:289699
		Link_domain_TSG_6_like	2198..2290	CDD:239592
		Fasciclin	2322..2448	CDD:295423
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900