DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and stab2

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_017210540.1	Gene:	stab2 / 565194	ZFINID:	ZDB-GENE-041210-336	Length:	2543	Species:	Danio rerio

Alignment Length:	144	Identity:	39/144 - (27%)
Similarity:	50/144 - (34%)	Gaps:	48/144 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 CCPGYRTILFGFCEPVCQEA-CPAHSYCAE----PDRCHCQRGYEPSHHHTTGHQL--------I 132
            |..|:    ||   |.|... |..|..|.|    ...|.|:.|:       ||.|.        :
Zfish  1990 CLDGH----FG---PDCNACNCTEHGSCDEGLQGTGSCFCEEGW-------TGPQCENKLADGPV 2040

  Fly   133 CRPVC--QGGCPEHSHCVAH-------------NECECWPG--FKDASSWFSLSLRCERVQCGHE 180
            |.|.|  :|.|.|::.||..             |.|:.|.|  .|||    ..|.:.|:|.|...
Zfish  2041 CNPACHEKGVCMENNTCVCKPFYEGDGITCTVANMCKYWNGGCSKDA----KCSQKGEKVSCACL 2101

  Fly   181 QRFDPGRRACVQIE 194
            |.|......|..|:
Zfish  2102 QGFSGDGFVCTPID 2115

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	37/140 (26%)
stab2	XP_017210540.1	EGF_3	239..268	CDD:289699
		Fasciclin	374..495	CDD:280607
		Fasciclin	518..643	CDD:280607
		EGF_3	824..855	CDD:289699
		EGF_3	910..941	CDD:289699
		Fasciclin	1000..1119	CDD:280607
		Fasciclin	1135..1252	CDD:280607
		EGF_3	1465..1501	CDD:289699
		EGF_3	1550..1586	CDD:289699
		Fasciclin	1616..1716	CDD:280607
		Fasciclin	1742..1873	CDD:280607
		EGF_3	2076..2111	CDD:289699	12/38 (32%)
		EGF_3	2117..2154	CDD:289699
		Link_Domain	2188..2280	CDD:295393
		FAS1	2345..2438	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900