DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and Stab2

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_038934441.1	Gene:	Stab2 / 282580	RGDID:	628822	Length:	2569	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	54/270 - (20%)
Similarity:	85/270 - (31%)	Gaps:	96/270 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MLVLVLMTIHLVEVSSLAITNG--------------------HCQKNISVKYQVPVAKTRMAGAG 53
            :|.|:.:.:.||..::.:.|.|                    .|..|.:||......|.....||
  Rat    11 LLPLIPLFLGLVVQNACSPTEGPELAKRCDKKSTLTIKTECQSCSANFAVKCPDGYIKVTSGSAG 75

  Fly    54 PPNASHPIDLDSYVV----YEERVRWDNIQ-VCCPGYRTILFGFCEPVCQEA-------CPAHSY 106
            ..:..:.:|:.|||:    .....|.|.:| .||||:    :|   |.|.|.       |.....
  Rat    76 VRDCRYSLDIQSYVLAIPGCRHICRKDYLQPQCCPGH----WG---PDCMECPGGARAPCGGRGV 133

  Fly   107 CAE----PDRCHCQRGYEPSHHHTTGHQLICRP-----------VCQGG---------------- 140
            |.|    ...|.||.|:..:.........:..|           ||..|
  Rat   134 CDEGMEGTGSCSCQAGFSGTACEACATDNVFGPNCSAVCSCVHGVCNSGLNGDGTCECLSAYRGP 198

  Fly   141 -------------CPEHSHCVAHN------ECECWPGFK-DASSWFSLSLRCERVQCGHEQR--- 182
                         |||:|.|...:      :|:|.|.:: |..:...:: .|.:..| |...
  Rat   199 KCDKPIPECATLLCPENSRCSPSSKDETKLQCKCLPNYEGDGHNCRPIN-PCLKTIC-HPHASCS 261

  Fly   183 -FDPGRRACV 191
             ..|.|.:|:
  Rat   262 YLGPNRHSCI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	30/169 (18%)
Stab2	XP_038934441.1	EGF_CA	254..283	CDD:419698	5/19 (26%)
		EGF_3	334..369	CDD:403986
		Fasciclin	390..512	CDD:396845
		Fasciclin	533..658	CDD:396845
		EGF_3	840..868	CDD:403986
		EGF_3	881..912	CDD:403986
		EGF_3	923..955	CDD:403986
		EGF_3	961..997	CDD:403986
		Fasciclin	1014..1133	CDD:396845
		Fasciclin	1152..1269	CDD:396845
		EGF_3	1478..1514	CDD:403986
		EGF_3	1520..1556	CDD:403986
		EGF_3	1562..1598	CDD:403986
		Fasciclin	1629..1729	CDD:396845
		Fasciclin	1754..1885	CDD:396845
		EGF_CA	2059..2084	CDD:419698
		EGF_3	2090..2125	CDD:403986
		EGF_3	2131..2168	CDD:403986
		Link_Domain	2202..2294	CDD:413401
		FAS1	2360..2449	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900