Protein Alignment NimC3 and DKK4

DIOPT Version :10

• Sequence 1: NP_524928.2
• Gene: NimC3 / 48772
• FlyBaseID: FBgn0001967
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_055235.1
• Gene: DKK4 / 27121
• HGNCID: 2894
• Length: 224
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 36/189 - (19%)
• Similarity: 52/189 - (27%)
• Gaps: 85/189 - (44%)

  Fly    72 RVRWDNIQVCCPGYRTILFGFCEPVC---QEACP-AHSYCAEPDRCHCQRGYEPSHHHTTGHQL- 131
            |.|.....:||||...:     ..||   ::|.| ......|.|..|.:        .||||.:
Human    70 RRRCQRDAMCCPGTLCV-----NDVCTTMEDATPILERQLDEQDGTHAE--------GTTGHPVQ 121

  Fly   132 -------------------------------------------ICRPVCQGG--CPEHSHCVAHN 151
                                                       ||:||...|  |....|
Human   122 ENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRGH----- 181

  Fly   152 ECECWPGFKDASSWFSLSLRCERVQCGHEQRFDPGRRACVQIEMSMEELMQRVAERLAK 210
                    ||.:....:..||:   ||      ||.....|:..:.:....||.:::.|
Human   182 --------KDTAQAPEIFQRCD---CG------PGLLCRSQLTSNRQHARLRVCQKIEK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	None
DKK4	NP_055235.1	Dkk4_Cys1	37..91	CDD:438007	7/25 (28%)
		DKK-type Cys-1	41..90		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..139		5/37 (14%)
		Dkk4_Cys2	128..221	CDD:438001	18/114 (16%)
		DKK-type Cys-2	145..218		17/94 (18%)