Protein Alignment NimC3 and DKK1

DIOPT Version :9

• Sequence 1: NP_524928.2
• Gene: NimC3 / 48772
• FlyBaseID: FBgn0001967
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_036374.1
• Gene: DKK1 / 22943
• HGNCID: 2891
• Length: 266
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 55/265 - (20%)
• Similarity: 79/265 - (29%)
• Gaps: 113/265 - (42%)

  Fly     7 YPMLVLVLMTIHLVEVSSLAITN---------GHCQKNISV----------KYQV-------PVA 45
            :|:|. |..|::.| ::|.||.|         ||....:|.          |||.       |.|
Human    24 HPLLG-VSATLNSV-LNSNAIKNLPPPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCA 86

  Fly    46 KTRMAGAGPPNASHPIDLDSYV-----VYEERVRWDNIQVCCPGYRTILFGFCEPVCQEACPAHS 105
            :....|.....||.....|:.|     ..:.|.|.....:||||      .:|:         :.
Human    87 EDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPG------NYCK---------NG 136

  Fly   106 YCAEPDRCHCQ------------------RGY------EPSHHHTTGHQ---------------- 130
            .|...|:.|.:                  .||      ....:||.|.:
Human   137 ICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCC 201

  Fly   131 ------LICRPVCQGG--CPEHSHCVAH-----NECECWPGFKDASSWFSLSLRCERVQCGHEQR 182
                  .||:||.:.|  |.:|....:|     ..|.|..|           |.| |:|..|.|.
Human   202 ARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG-----------LSC-RIQKDHHQA 254

  Fly   183 FDPGR 187
            .:..|
Human   255 SNSSR 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	27/156 (17%)
DKK1	NP_036374.1	Dickkopf_N	85..139	CDD:309719	13/68 (19%)
		DKK-type Cys-1	85..138		13/67 (19%)
		DKK-type Cys-2	189..263		18/83 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900