DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and Stab1

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_619613.2	Gene:	Stab1 / 192187	MGIID:	2178742	Length:	2571	Species:	Mus musculus

Alignment Length:	140	Identity:	42/140 - (30%)
Similarity:	56/140 - (40%)	Gaps:	47/140 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 IQV--CCPGYRTILFG-FCEPVCQ----EACPAHSYCAEPDR------CHCQRGYEPSHHHTTGH 129
            |||  ||||:    || .||| |.    ..|..|..|  .||      |.||.|:     |.|..
Mouse  1316 IQVPDCCPGF----FGTLCEP-CPGGLGGVCSGHGQC--QDRFLGNGECRCQEGF-----HGTAC 1368

  Fly   130 QLICR-----PVCQGGCP-EHSHCV----AHNECECWPGFKDASSWFSLSLRCERVQCGHE--QR 182
            :: |.     |.|.|.|. :|..|.    .:..|.|..|::        .|||::....|:  ::
Mouse  1369 EM-CELGRYGPTCSGVCDCDHGLCQEGLRGNGSCVCHAGWQ--------GLRCDQKITDHQCPKK 1424

  Fly   183 FDPGRRACVQ 192
            .||... |:|
Mouse  1425 CDPNAN-CIQ 1433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	35/131 (27%)
Stab1	NP_619613.2	Fasciclin	520..644	CDD:280607
		EGF_3	915..946	CDD:289699
		EGF_3	952..988	CDD:289699
		Fasciclin	1000..1121	CDD:280607
		EGF_3	1460..1496	CDD:289699
		EGF_3	1502..1539	CDD:289699
		EGF_3	1545..1582	CDD:289699
		Fasciclin	1607..1711	CDD:280607
		Fasciclin	1737..1867	CDD:280607
		EGF_Lam	<1992..2021	CDD:214543
		EGF_3	2095..2130	CDD:289699
		EGF_3	2136..2173	CDD:289699
		Link_Domain	2208..2300	CDD:295393
		FAS1	2367..2463	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900