Sequence 1: | NP_004637.1 | Gene: | NPHS1 / 4868 | HGNCID: | 7908 | Length: | 1241 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001247334.1 | Gene: | side / 43300 | FlyBaseID: | FBgn0016061 | Length: | 986 | Species: | Drosophila melanogaster |
Alignment Length: | 871 | Identity: | 197/871 - (22%) |
---|---|---|---|
Similarity: | 302/871 - (34%) | Gaps: | 229/871 - (26%) |
- Green bases have known domain annotations that are detailed below.
Human 407 RREDNGLT----------LTC----EAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKLRA 457
Human 458 GTRVRLVCLAIGGNPEPS---LMWYKDSRTVTESRLPQESRRVHLGSVEKSGSTFSRELVLVTG- 518
Human 519 -PSDNQAK-----------FTCKAGQLSASTQ-----LAVQFPPTNVTIL--------ANASALR 558
Human 559 PGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFKGSAA-ARSVLLQVSSRD-HGQRV 621
Human 622 TCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSV-----SANPAPEAFNW 681
Human 682 TFRGYRLSPAGGPRHRILSSG----ALHLWNVTRADDGLYQLHCQN-----SEGTAEARLRLDVH 737
Human 738 YAPTIR---ALQDPTEVNV---GGSVDIVCTVDANPILPGMFNW-----ERLGEDEEDQSLDDME 791
Human 792 KISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFAPQVEHPTPLTKVAAAGDST 856
Human 857 SSATLHCRARGVP--NIVFTWTKNGV----PL---DLQDPRYTEHTYHQGGVHSSLLTIANVSAA 912
Human 913 QDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLTPHSVGLE--WKPGFDGGLPQRFCI 975
Human 976 RY-----------------------EALGTPGFHYVDVVPPQATT------------FTLTGLQP 1005
Human 1006 STRYRVWLLASNALGDSGLADKGTQLPITTP--------GLHQPSGEPEDQLPTEPP-------- 1054
Human 1055 ---------------SGP---SGLPLLPVLFALGGLLLLSNASCVGGVLWQRRLRRLAEGISE-- 1099
Human 1100 ------KTEAGS---EEDRVRNEYEE 1116 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
NPHS1 | NP_004637.1 | V-set | 38..119 | CDD:284989 | |
IG_like | 38..113 | CDD:214653 | |||
C2-set_2 | 141..228 | CDD:285423 | |||
Ig | 240..321 | CDD:299845 | |||
IG_like | 254..336 | CDD:214653 | |||
Ig | 345..424 | CDD:299845 | 9/30 (30%) | ||
Ig | 445..530 | CDD:299845 | 19/100 (19%) | ||
I-set | 446..541 | CDD:254352 | 20/115 (17%) | ||
Ig | 549..632 | CDD:299845 | 22/92 (24%) | ||
IG_like | 558..642 | CDD:214653 | 21/85 (25%) | ||
I-set | 646..736 | CDD:254352 | 21/103 (20%) | ||
Ig | 662..736 | CDD:299845 | 17/87 (20%) | ||
Ig_3 | 739..820 | CDD:290638 | 23/91 (25%) | ||
IG_like | 748..821 | CDD:214653 | 19/80 (24%) | ||
Ig8_hNephrin_like | 834..942 | CDD:143250 | 30/116 (26%) | ||
IG_like | 845..935 | CDD:214653 | 23/98 (23%) | ||
fn3 | 942..1023 | CDD:278470 | 29/117 (25%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1025..1057 | 8/62 (13%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1099..1137 | 9/29 (31%) | |||
Binds to NPHS2 | 1160..1241 | ||||
side | NP_001247334.1 | V-set | 95..211 | CDD:284989 | 23/130 (18%) |
IG_like | 100..211 | CDD:214653 | 21/119 (18%) | ||
Ig | 235..301 | CDD:299845 | 17/68 (25%) | ||
Ig | 326..408 | CDD:299845 | 16/83 (19%) | ||
IG_like | 329..407 | CDD:214653 | 15/79 (19%) | ||
IG_like | 435..511 | CDD:214653 | 21/92 (23%) | ||
Ig_2 | 442..511 | CDD:290606 | 21/85 (25%) | ||
FN3 | <700..735 | CDD:238020 | 11/41 (27%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3515 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |