| Sequence 1: | NP_004637.1 | Gene: | NPHS1 / 4868 | HGNCID: | 7908 | Length: | 1241 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_722953.1 | Gene: | CG31773 / 326159 | FlyBaseID: | FBgn0051773 | Length: | 758 | Species: | Drosophila melanogaster |
| Alignment Length: | 647 | Identity: | 121/647 - (18%) |
|---|---|---|---|
| Similarity: | 206/647 - (31%) | Gaps: | 213/647 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Human 400 SNLTFLARREDN---GLTLTCEAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKLRAGTRV 461
Human 462 RLVCLAIGGNPEPSLMWYKDSRTVTESRLPQESRRVH-----LGSVEKSGSTFSRELVLVTGPS- 520
Human 521 -----DNQAKFTCKA-------GQLSASTQLAVQFPPTNVTILA-NASALRPGDALNLTCVSVSS 572
Human 573 NPPVNLSWDKEGERLEGVAAPPRRAPFKGSAAARSVLLQVSSRDHGQRVTCRAHSAELRETVSSF 637
Human 638 YRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSSG 702
Human 703 ALHLWNVTRADDGLYQLH----CQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTV 763
Human 764 DANPILPGMFNWERLGEDEEDQSLDDMEKISRGPTGR----------LRIHHAKLAQAGAYQCIV 818
Human 819 DNGVAPPARRLLRLVVRFAPQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFT---WTKNGV 880
Human 881 PLDLQ-DPRYTE-------HTYHQGGVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVS 937
Human 938 ISRPDPPSGLKVVSLTPHSVGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFT 999 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NPHS1 | NP_004637.1 | V-set | 38..119 | CDD:284989 | |
| IG_like | 38..113 | CDD:214653 | |||
| C2-set_2 | 141..228 | CDD:285423 | |||
| Ig | 240..321 | CDD:299845 | |||
| IG_like | 254..336 | CDD:214653 | |||
| Ig | 345..424 | CDD:299845 | 7/26 (27%) | ||
| Ig | 445..530 | CDD:299845 | 13/95 (14%) | ||
| I-set | 446..541 | CDD:254352 | 16/112 (14%) | ||
| Ig | 549..632 | CDD:299845 | 20/83 (24%) | ||
| IG_like | 558..642 | CDD:214653 | 18/83 (22%) | ||
| I-set | 646..736 | CDD:254352 | 17/93 (18%) | ||
| Ig | 662..736 | CDD:299845 | 16/77 (21%) | ||
| Ig_3 | 739..820 | CDD:290638 | 16/90 (18%) | ||
| IG_like | 748..821 | CDD:214653 | 13/82 (16%) | ||
| Ig8_hNephrin_like | 834..942 | CDD:143250 | 21/118 (18%) | ||
| IG_like | 845..935 | CDD:214653 | 21/100 (21%) | ||
| fn3 | 942..1023 | CDD:278470 | 9/58 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1025..1057 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1099..1137 | ||||
| Binds to NPHS2 | 1160..1241 | ||||
| CG31773 | NP_722953.1 | folC | 309..745 | CDD:273659 | 45/262 (17%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3515 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||