Protein Alignment Act87E and ACTR8

DIOPT Version :9

• Sequence 1: NP_001287314.1
• Gene: Act87E / 48632
• FlyBaseID: FBgn0000046
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_075050.3
• Gene: ACTR8 / 93973
• HGNCID: 14672
• Length: 624
• Species: Homo sapiens
• Alignment Length: 579
• Identity: 98/579 - (16%)
• Similarity: 186/579 - (32%)
• Gaps: 235/579 - (40%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRH--QG---------------------------- 43
            :|:..||...:.|.|.|..|.:: |.::.| ||  ||
Human    49 IVIHPGSTTLRIGRATDTLPASI-PHVIAR-RHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLK 111

  Fly    44 -----------------VMVGMGQKDSY---------------------------VGDEA----- 59
                             :.|...|..||                           ||:||
Human   112 MVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNP 176

  Fly    60 --------QSKRGILTLKYPIEHGIITN-WDDMEKIWHHTFYNELRVAPEE----HPVLLTEAPL 111
                    ..:||.|.: :|...|.:|. ..|:|.||.|.....|.:..::    ..:||.....
Human   177 LDCYNIHWPIRRGQLNI-HPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIY 240

  Fly   112 NPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAI 176
            |.:..:|.:..|:.: .....:.|..::|.:.|.||.::..::|.||..:....:.:|  :.|..
Human   241 NKQHVKELVNMILMK-MGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDG--VSHRN 302

  Fly   177 LRLDLA--GRDLTDYLMKILTERGYSF-----TTTAEREIVRDIKEKLCYVALDFEQEMATAAAS 234
            .||.||  |.|::.....::...|:.:     |...:..:::.:||..|::..|.         |
Human   303 TRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDI---------S 358

  Fly   235 TSLEKSYEL--PDGQVI----TIGNERFRCPESLFQPSFLGM----------------------- 270
            ...:..:::  ||...:    .:|:|:.:.|.:||.|:..|:
Human   359 GLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEH 423

  Fly   271 ----------------------------------------------------------------- 270
                                                                             
Human   424 YLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSAQGDGLMAGNDSE 488

  Fly   271 ------------------ESCGIHETVYNSIMKCDV-DIRKDLYANIVMSGGTTMYPGIADRMQK 316
                              ::.|:.:.:.:||..|.. |.:|.:|::|::.||..|:....:.:|.
Human   489 EALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQH 553

  Fly   317 EITALAPSTIK-----IKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESG 367
            .|....|.:.:     :.:|..|   :.:...|.||::||.|.|.|::||.::|:...|
Human   554 RILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFG 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act87E	NP_001287314.1	PTZ00281	1..376	CDD:173506	98/579 (17%)
ACTR8	NP_075050.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		NBD_sugar-kinase_HSP70_actin	162..619	CDD:388382	81/464 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	430..462		0/31 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810