DRSC/TRiP Functional Genomics Resources

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Protein Alignment Act87E and POTEF

DIOPT Version :10

Sequence 1:NP_477091.1 Gene:Act87E / 48632 FlyBaseID:FBgn0000046 Length:376 Species:Drosophila melanogaster
Sequence 2:XP_016860322.1 Gene:POTEF / 728378 HGNCID:33905 Length:1085 Species:Homo sapiens


Alignment Length:373 Identity:330/373 - (88%)
Similarity:348/373 - (93%) Gaps:0/373 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 DDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILT 67
            ||:.|.||:|||||||||||||||||||||||||||||.||:|.||.||:||||.||||||||||
Human   712 DDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILT 776

  Fly    68 LKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPA 132
            ||||:|||||||||||||||||||||||||||||||||||||.|||||||||||||||||||.||
Human   777 LKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEATLNPKANREKMTQIMFETFNTPA 841

  Fly   133 MYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTER 197
            ||||||||||||.||||||||:||||||:||||||||.|||||.||||||||:|.|||||||||.
Human   842 MYVAIQAVLSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTEH 906

  Fly   198 GYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESL 262
            ||.|||.||||||||||||||||||||||||||.|:|:|||||||||||||||||||||||||:|
Human   907 GYRFTTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEAL 971

  Fly   263 FQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIK 327
            |||.||||||||||||.:|||||.|||||||||.|.|:|||||||||:|.||||||.|||||.:|
Human   972 FQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMK 1036

  Fly   328 IKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKC 375
            |:|||||:||||||:||||||||||||||||||||||||||.||||||
Human  1037 IRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 1084

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Act87ENP_477091.1 ASKHA_NBD_actin 7..371 CDD:466823 322/363 (89%)
POTEFXP_016860322.1 ANKYR 138..378 CDD:440430
ANK repeat 174..203 CDD:293786
ANK repeat 205..246 CDD:293786
ANK repeat 248..279 CDD:293786
ANK repeat 281..312 CDD:293786
ANK repeat 314..345 CDD:293786
CCDC144C 658..>711 CDD:464371
ASKHA_NBD_actin 716..1080 CDD:466823 322/363 (89%)
Blue background indicates that the domain is not in the aligned region.

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