Protein Alignment Act87E and ACTR3B

DIOPT Version :9

• Sequence 1: NP_001287314.1
• Gene: Act87E / 48632
• FlyBaseID: FBgn0000046
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_065178.1
• Gene: ACTR3B / 57180
• HGNCID: 17256
• Length: 418
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 151/416 - (36%)
• Similarity: 224/416 - (53%)
• Gaps: 59/416 - (14%)

  Fly    10 VVDNGSGMCKAGFAGDDAPRAVFPS---------IVGRPRHQGVMVGMGQKDSYVGDEAQSKRGI 65
            |||.|:|..|.|:||:..|:.:.||         :|.:.:.: |:.|:...|.::||||..|...
Human     9 VVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRR-VLRGVDDLDFFIGDEAIDKPTY 72

  Fly    66 LTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNA 130
            .| |:||.||||.:||.||:......:..||..||:|..|:||.|||...|||.:.:||||:||.
Human    73 AT-KWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNV 136

  Fly   131 PAMYVAIQAVLSLYAS-------GRT-TGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLT 187
            |.:|:|:||||:|.||       .|| ||||:||||||:|.:|:.|||.:...|..:.:||||:|
Human   137 PGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201

  Fly   188 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMAT------------AAASTSLEKS 240
            .::.::|.||..........|..:.||||.||:..|..:|.|.            ...:...:|.
Human   202 YFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDVDPRKWIKQYTGINAINQKK 266

  Fly   241 YELPDGQVITIGNERFRCPESLFQPSFLG---MESCGIHETVYNSIMKCDVDIRKDLYANIVMSG 302
            :      ||.:|.|||..||..|.|.|..   |||  |.:.|...|..|.:|:|:.||.|:|:||
Human   267 F------VIDVGYERFLGPEIFFHPEFANPDFMES--ISDVVDEVIQNCPIDVRRPLYKNVVLSG 323

  Fly   303 GTTMYPGIADRMQKEIT----------------ALAPSTIKIKIIAPPERKYSVWIGGSILASLS 351
            |:||:.....|:|:::.                .:.|..::::::....::|:||.|||:|||..
Human   324 GSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVVTHHMQRYAVWFGGSMLASTP 388

  Fly   352 TFQQMWISKQEYDESGPGIV-HRKCF 376
            .|.|:..:|::|:|.||.|. |...|
Human   389 EFFQVCHTKKDYEEYGPSICRHNPVF 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act87E	NP_001287314.1	PTZ00281	1..376	CDD:173506	150/414 (36%)
ACTR3B	NP_065178.1	PTZ00280	2..417	CDD:240343	151/416 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820