DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Act87E and si:ch211-241j12.3

DIOPT Version :9

Sequence 1:	NP_001287314.1	Gene:	Act87E / 48632	FlyBaseID:	FBgn0000046	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_017207998.2	Gene:	si:ch211-241j12.3 / 566552	ZFINID:	ZDB-GENE-040724-72	Length:	1245	Species:	Danio rerio

Alignment Length:	375	Identity:	195/375 - (52%)
Similarity:	272/375 - (72%)	Gaps:	7/375 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTL 68
            |....:|:|:|||:.|||||..|.|.||||:::|||:::.||.....::.|||.:||..||:|||
Zfish   876 DYKTPIVLDSGSGLMKAGFADQDLPAAVFPTVIGRPKYEEVMNSCVDRELYVGHDAQHMRGVLTL 940

  Fly    69 KYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAM 133
            :|||.||:::|||:||.:|.|.| ..|..|||:||||||||.|||..||::|.::|||.|:.|..
Zfish   941 RYPIRHGVVSNWDEMEMLWTHAF-QLLSAAPEDHPVLLTEAALNPLQNRQRMVELMFEAFSVPLT 1004

  Fly   134 YVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERG 198
            :||:||||:|||||||||:||||||||||:||::|||.||||:.||||||.|:|..|.|:|.|.|
Zfish  1005 FVAVQAVLALYASGRTTGVVLDSGDGVSHSVPVFEGYCLPHAVQRLDLAGADVTLQLQKLLLESG 1069

  Fly   199 YSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLF 263
            ....|:||.||||::||:.|:|::|:|.||    .|:..|..|.||||..:.:.::|||.||.||
Zfish  1070 VCLRTSAELEIVREMKERCCFVSVDYEAEM----KSSESEIQYTLPDGHTVPLASQRFRAPEILF 1130

  Fly   264 QPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIK- 327
            :|..:|.:..|:||:|:.||::.|:|:|:....||::|||.|:..|:|:|:|.|:.|:.|..:.
Zfish  1131 RPELIGRDHYGLHESVFRSILQSDLDLRRSFVGNILLSGGNTLLSGLAERLQLEVRAMVPLDLSA 1195

  Fly   328 -IKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
             :::.:||:|.:|||.||:.||||...|..|||..||:|.||.||.||||
Zfish  1196 CVRVSSPPDRDFSVWSGGAALASLPEQQSAWISAAEYEEFGPQIVFRKCF 1245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Act87E	NP_001287314.1	PTZ00281	1..376	CDD:173506	193/373 (52%)
si:ch211-241j12.3	XP_017207998.2	Neuromodulin_N	<411..625	CDD:331332
si:ch211-241j12.3	XP_017207998.2	ACTIN	878..1245	CDD:214592	192/371 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11937
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020