Protein Alignment Act87E and ACTR1B

DIOPT Version :10

• Sequence 1: NP_477091.1
• Gene: Act87E / 48632
• FlyBaseID: FBgn0000046
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005726.1
• Gene: ACTR1B / 10120
• HGNCID: 168
• Length: 376
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 203/370 - (54%)
• Similarity: 279/370 - (75%)
• Gaps: 7/370 - (1%)

  Fly     9 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73
            :|:|||||:.|||||||..|:..||:.||||:|..||.|..:.|.::|.:|:..||:||::||:|
Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPME 76

  Fly    74 HGIITNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAI 137
            ||::.:|:|||:||.:.: .::|:...||||||||||||||..||||..::.|||||.||:::::
Human    77 HGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISM 141

  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202
            ||||||||:|||||:||||||||:|.||||||:|:||:|:|:|:||||::.||..:|.:.|..|.
Human   142 QAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFH 206

  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEK-SYELPDGQVITIGNERFRCPESLFQPS 266
            |:||.|:||.|||:.||::::.:::.|     ...|| .|.||||..:.:|..|||.||.||||.
Human   207 TSAEFEVVRTIKERACYLSINPQKDEA-----LETEKVQYTLPDGSTLDVGPARFRAPELLFQPD 266

  Fly   267 FLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKII 331
            .:|.||.|:||.|..:|.|.|:|:|:.|:||||:|||:|::.|..||:..|:..|||..|||||.
Human   267 LVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKIS 331

  Fly   332 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376
            ||.||.||.||||||||||.||::||:||:||:|.|...:|||.|
Human   332 APQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act87E	NP_477091.1	ASKHA_NBD_actin	7..371	CDD:466823	199/363 (55%)
ACTR1B	NP_005726.1	ASKHA_NBD_Arp1	9..375	CDD:466820	201/367 (55%)