Protein Alignment Hsp70Bc and hscA

DIOPT Version :10

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 612
• Identity: 234/612 - (38%)
• Similarity: 351/612 - (57%)
• Gaps: 43/612 - (7%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |.|||||||.|.|...:.|:.|.:|:.:|....||.|.:......:|..|:...|::..||:...
E. coli    21 AAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSV 85

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKV-VSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||:||...|  |.:...|.|::. .|:.|.|.|    :..:....|..:|:.:|..:...|...
E. coli    86 KRLMGRSLAD--IQQRYPHLPYQFQASENGLPMI----ETAAGLLNPVRVSADILKALAARATEA 144

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            |...:...||||||||:|:|||.||||..:|||:|||::|||||||:|||||...:|.  :.::|
E. coli   145 LAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGV--IAVYD 207

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||:|||.:..| :|||.:|.||:.|||:|||:.|..::.|:.....    ||:.|..|.|
E. coli   208 LGGGTFDISILRLSRG-VFEVLATGGDSALGGDDFDHLLADYIREQAGIPD----RSDNRVQREL 267

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            ..||..||..||.:...|:.: |.::|:     :||.:|.||.|.|.:.||....:||.||.::.
E. coli   268 LDAAIAAKIALSDADSVTVNV-AGWQGE-----ISREQFNELIAPLVKRTLLACRRALKDAGVEA 326

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .::.::|:||||||:|.|:..:.||| |:....||:||:.||.|||:||.||.|::..  .::||
E. coli   327 DEVLEVVMVGGSTRVPLVRERVGEFF-GRPPLTSIDPDKVVAIGAAIQADILVGNKPD--SEMLL 388

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.|||||:||.||::.|:|.||..||..:.:.|:|:.|.|..:||.|.:|||.:.:|..:|..
E. coli   389 LDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLAR 453

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |.|.|||..|.|...|.|||.:||:|:|:|:|.|.|||...:|.:|...| |:.:||..|:.::.
E. coli   454 FALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYG-LTDSEIASMIKDSM 517

  Fly   522 KYADEDEKHR----QRITSRNALES----------YVFNVKQSVEQAPAGKLDEADKNSVLDKCN 572
            .||::|.|.|    |::.:...|||          .:...::.|....|..|.|..:...:|...
E. coli   518 SYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAAAHLSEVAQGDDVDAIE 582

  Fly   573 ETIRWLDSNTTAEKEEF-DHKMEELTR 598
            :.|:.:|..|    ::| ..:|::..|
E. coli   583 QAIKNVDKQT----QDFAARRMDQSVR 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	234/612 (38%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	234/612 (38%)