Protein Alignment Hsp70Bc and SSA1

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_009396.2
• Gene: SSA1 / 851259
• SGDID: S000000004
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 646
• Identity: 453/646 - (70%)
• Similarity: 535/646 - (82%)
• Gaps: 14/646 - (2%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |:|||||||||||..:.:.:|:|||||||||||||:|||||:||||||.||||.||||.||||||
Yeast     4 AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDA 68

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||.::||::..||||:|||::...|||:|.||:|||:|.|.||:||||||.|||||||:||
Yeast    69 KRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYL 133

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..:.|||:||||||||||||||||||.|||||||||||||||||:||||||..| |.:||||||
Yeast   134 GAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGK-EEHVLIFDL 197

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:|:|::| :|||::|||||||||||||||||.|..:|||||.||||.:|.|||||||
Yeast   198 GGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLR 261

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||.:.::|||:||||.||||.::|||||||||||||:||.||||.|.|||:||.
Yeast   262 TACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKS 326

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            |:.:||||||||||||||.|:.::|:||..|.|||||||||||||||||||:||:|.|.||:||:
Yeast   327 QVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLL 391

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||||||||||||||||||||.||..||.|:::.||||:||||||.|||:|||||.|||||.||.|
Yeast   392 DVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKF 456

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|||||||||||||||||||:|:||||||||.|..|||:..|||.|||||||:.:|::||.||||
Yeast   457 ELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEK 521

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKE 587
            :.:||||..|||.|:|.|||..:::|.::.:| ..||::|||::|..|..|||.||||||||.||
Yeast   522 FKEEDEKESQRIASKNQLESIAYSLKNTISEA-GDKLEQADKDTVTKKAEETISWLDSNTTASKE 585

  Fly   588 EFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGG-------YSGPTVEEVD 641
            |||.|::||....:|||:|::|.|    |.||...|...|||.|       ..||||||||
Yeast   586 EFDDKLKELQDIANPIMSKLYQAG----GAPGGAAGGAPGGFPGGAPPAPEAEGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	451/644 (70%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	282/375 (75%)
SSA1	NP_009396.2	PTZ00009	4..642	CDD:240227	451/644 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		mtm9161
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720