Protein Alignment Hsp70Bc and hspa12b

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001036151.1
• Gene: hspa12b / 735291
• ZFINID: ZDB-GENE-070226-1
• Length: 691
• Species: Danio rerio
• Alignment Length: 669
• Identity: 138/669 - (20%)
• Similarity: 235/669 - (35%)
• Gaps: 204/669 - (30%)

  Fly     4 IGIDLGTT---YSCVGVYQHGKVEIIANDQG------NRTTPSYVAFTDSERLIGDPAKNQVAMN 59
            :.||.|||   |:...:.....:.::...:|      |:.:|:.:..|...|.      :.....
Zfish    63 VAIDFGTTSSGYAFSFIEDPETIHMMRRWEGGDPGVANQKSPTCLLLTPDLRF------HSFGFA 121

  Fly    60 PRNTVFDAKRLIGRKYDDPKIAEDMKHW----PFKV----VSD----------GGKPKIGVEYKG 106
            .|::..|.         ||   |:.:||    .||:    .||          .|:....:|...
Zfish   122 ARDSYHDL---------DP---EEARHWLYFDKFKMKIHSTSDLTMETELESVSGRRVQAIEVFA 174

  Fly   107 ESKRFAPEEISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------N 165
            .:.||..|.    .|.::|:.:.:.|..:....||||||.:....:|..::|.::|||      .
Zfish   175 HALRFFREH----ALKEVKDQSSSVLEGNEVRWVITVPAVWRQPAKQFMREAAYLAGLVPPDSPE 235

  Fly   166 VLRIINEPTAAAL------------------AYGLDKNLKGER---------------------- 190
            .|.|..||.||::                  ..|.|  :.|.|
Zfish   236 QLLIALEPEAASIYCRKLRLHQVTDLSQRPVTNGFD--IDGSRPFDSSFRQAREQLRRARHSRTF 298

  Fly   191 -----------------NVLIFDLGGGTFDVSILTID--EGSLFEVRSTAGDTHLGGEDFDNRLV 236
                             ..::.|.||||.|:::..|:  :|:|.|:...:|..: |....|....
Zfish   299 LVESGTGELWSEMQTGDRYIVADCGGGTVDLTVHQIEQPQGTLKELYKASGGPY-GAVGVDLAFE 362

  Fly   237 THLAEEFKRKYKKDLRS-NPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFY-------- 292
            |.|.:.|...:....:: .|.|...|..|.|..|||.:.....|:.|...|...|||
Zfish   363 TMLCQIFGTDFIDSFKAKRPAAWVDLTIAFEARKRTAAPGRANTLNISLPFSFIDFYKQHRGQSV 427

  Fly   293 ---TKVSRARF------------EELCADLFRNTLQPVEKALNDAKMDKGQIHDI---VLVGGST 339
               .:.|...|            .|...:||:.|:..:.|.:.:. |.|.::..:   .||||..
Zfish   428 ETALRKSNMNFIKWSSQGMLRLSTEATNELFQPTINNIIKHIENV-MQKEEVKGVRFLFLVGGFA 491

  Fly   340 RIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGIET 403
            ..|.:|..:|... |:|..:.|..|..:   ..::.|:|.| |.:     |:.|...||:.|:
Zfish   492 ESPMLQRAIQNTL-GRNCRIIIPHDVGL---TILKGAVLFGLDPT-----VVRVRRCPLTYGV-- 545

  Fly   404 AGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEG--------ERAMTKDNN-ALGTFDL 459
              ||:.:.:|                 ...|...:.:.:|        :|.::.|.: |||....
Zfish   546 --GVLNRFVE-----------------GRHPHDKLLIKDGREWCTDILDRFVSVDQSVALGEVVR 591

  Fly   460 SGIPPAPRGVPQI----------EVTFDLDAN----GILNVSAKEMSTGKAKNITIKNDKGRLSQ 510
            ....||..|..:|          ::|:..|..    |.:.:...|  :|:|...|..||||...:
Zfish   592 RSYTPARMGQRKIIINIYCSDTDDITYITDPGVRKCGAITLDLLE--SGEASASTGDNDKGSAFE 654

  Fly   511 AEIDRMVNEAEKYADEDEK 529
            .   |.:....::.|.:.|
Zfish   655 R---REIRTTMQFGDTEIK 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	138/669 (21%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	102/493 (21%)
hspa12b	NP_001036151.1	HSPA12B_like_NBD	61..529	CDD:212686	103/495 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910