Protein Alignment Hsp70Bc and hsph1

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_001919957.2
• Gene: hsph1 / 557824
• ZFINID: ZDB-GENE-120410-4
• Length: 901
• Species: Danio rerio
• Alignment Length: 709
• Identity: 203/709 - (28%)
• Similarity: 351/709 - (49%)
• Gaps: 110/709 - (15%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|.|:|....|:.|.:.|.:|.::|:..:|.|||.::|....|.||:.||||:..||.:|||
Zfish    63 MAVVGFDVGFQNCCIAVVKSGGIETVSNEFTDRCTPSVISFGSKNRAIGNAAKNQMITNPSSTVF 127

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVE--YKGESKRFAPEEISSMVLTKMKE 126
            ..|||..|.|.|..:..:..:.|:.:|  :||   |:||:  |..:...|:.|:||:|:|||:|:
Zfish   128 HFKRLHSRLYHDKVVQAEKANLPYDLVPLNDG---KVGVQVMYLDQEHHFSIEQISAMLLTKLKD 189

  Fly   127 TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK-NLKGE- 189
            .|||.|.:.:.:.||::|::|.||:|::..||..|||||.|:::|:.||.||.||:.| :|.|.
Zfish   190 IAEANLQKKVLECVISIPSFFTDSERRSVLDAAKIAGLNCLKLMNDSTAVALNYGIYKEDLPGSD 254

  Fly   190 ---RNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDL 251
               :.|...|||...|.|||...:.|.: :|.|||.|.:|||:|||.|||.|...|||.||..|:
Zfish   255 ENPKIVAFVDLGHSAFQVSICAFNRGKV-KVLSTAFDPYLGGKDFDQRLVDHFCAEFKSKYMMDV 318

  Fly   252 RSNPRALRRLRTAAERAKRTLSS-STEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPV 315
            :|..|||.||....|:.|:.:|| |||.::.|:...:.:|...:::||:|||:||||.......:
Zfish   319 KSKTRALLRLTQECEKLKKLMSSNSTELSLNIECFIDDKDVCGRMNRAKFEEMCADLIERVKFTL 383

  Fly   316 EKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            .||:..|.:....|..:.:|||:||||.|::.:..||. ::::.::|.|||||.|.|:|.|:||
Zfish   384 MKAVEQAGVRLQDISAVEIVGGATRIPAVKAQISSFFR-RDVSTTLNADEAVARGCALQCAMLS- 446

  Fly   381 DQSGKIQDVLLVDVAPLSLGIETA-----GGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQV 440
             .:.::::..:.||.|..:.:..:     |....::..||  .||...|..:.|. |:|.:....
Zfish   447 -PAFRVREFSITDVIPFPISLSWSSEADEGKSCHEIFSRN--HPCPSAKMITFYR-NKPFILEAF 507

  Fly   441 YEGERAMTKDNNALGTFDLSGIPPAP-RGVPQIEVTFDLDANGILNVSAK--------------- 489
            |..:.::......:|.:.:..|.|.. |...:::|..:::.:|:::||:.
Zfish   508 YSDKSSLPFPEAKIGEYKVQNIQPQENREKAKVKVKVEVNRSGVVSVSSAAVVLRVRSDESEITE 572

  Fly   490 -------------------------EMSTG----------------------------------- 494
                                     |:|..
Zfish   573 INEDVDSHDASDDTDVQDKTEEVNIELSVNKENLPTAQCPPMEKEQNQRETLSMNGEVNSHPPHA 637

  Fly   495 -----KAKNITIKNDKGRLSQAEIDRM---VNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV 551
                 |.|::.:..::....|...||:   ..:..|...:|.:.::|..::||:|..|:..:..:
Zfish   638 KKAKMKVKHVVLPMEETFNQQLPKDRLSAYTEQENKMIQQDRQEKERNNAKNAVEENVYYFRHKL 702

  Fly   552 EQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTKMHQ 609
            |.:....|:..:..:..:..|.|..|| |.....:|:.:.:::.|:.:...|:..:..:
Zfish   703 EGSYQTFLNAQEHQAFSELLNGTENWLYDEGADQDKQTYINRLAEIHKLGLPVENRYRE 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	202/708 (29%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	155/385 (40%)
hsph1	XP_001919957.2	HSPH1_NBD	64..446	CDD:212689	155/386 (40%)
		HSP70	65..761	CDD:278441	202/705 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810