Protein Alignment Hsp70Bc and hsph1

DIOPT Version :10

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_001919957.3
• Gene: hsph1 / 557824
• ZFINID: ZDB-GENE-120410-4
• Length: 866
• Species: Danio rerio
• Alignment Length: 709
• Identity: 203/709 - (28%)
• Similarity: 351/709 - (49%)
• Gaps: 110/709 - (15%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|.|:|....|:.|.:.|.:|.::|:..:|.|||.::|....|.||:.||||:..||.:|||
Zfish    28 MAVVGFDVGFQNCCIAVVKSGGIETVSNEFTDRCTPSVISFGSKNRAIGNAAKNQMITNPSSTVF 92

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVE--YKGESKRFAPEEISSMVLTKMKE 126
            ..|||..|.|.|..:..:..:.|:.:|  :||   |:||:  |..:...|:.|:||:|:|||:|:
Zfish    93 HFKRLHSRLYHDKVVQAEKANLPYDLVPLNDG---KVGVQVMYLDQEHHFSIEQISAMLLTKLKD 154

  Fly   127 TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK-NLKGE- 189
            .|||.|.:.:.:.||::|::|.||:|::..||..|||||.|:::|:.||.||.||:.| :|.|.
Zfish   155 IAEANLQKKVLECVISIPSFFTDSERRSVLDAAKIAGLNCLKLMNDSTAVALNYGIYKEDLPGSD 219

  Fly   190 ---RNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDL 251
               :.|...|||...|.|||...:.|.: :|.|||.|.:|||:|||.|||.|...|||.||..|:
Zfish   220 ENPKIVAFVDLGHSAFQVSICAFNRGKV-KVLSTAFDPYLGGKDFDQRLVDHFCAEFKSKYMMDV 283

  Fly   252 RSNPRALRRLRTAAERAKRTLSS-STEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPV 315
            :|..|||.||....|:.|:.:|| |||.::.|:...:.:|...:::||:|||:||||.......:
Zfish   284 KSKTRALLRLTQECEKLKKLMSSNSTELSLNIECFIDDKDVCGRMNRAKFEEMCADLIERVKFTL 348

  Fly   316 EKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            .||:..|.:....|..:.:|||:||||.|::.:..||. ::::.::|.|||||.|.|:|.|:||
Zfish   349 MKAVEQAGVRLQDISAVEIVGGATRIPAVKAQISSFFR-RDVSTTLNADEAVARGCALQCAMLS- 411

  Fly   381 DQSGKIQDVLLVDVAPLSLGIETA-----GGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQV 440
             .:.::::..:.||.|..:.:..:     |....::..||  .||...|..:.|. |:|.:....
Zfish   412 -PAFRVREFSITDVIPFPISLSWSSEADEGKSCHEIFSRN--HPCPSAKMITFYR-NKPFILEAF 472

  Fly   441 YEGERAMTKDNNALGTFDLSGIPPAP-RGVPQIEVTFDLDANGILNVSAK--------------- 489
            |..:.::......:|.:.:..|.|.. |...:::|..:::.:|:::||:.
Zfish   473 YSDKSSLPFPEAKIGEYKVQNIQPQENREKAKVKVKVEVNRSGVVSVSSAAVVLRVRSDESEITE 537

  Fly   490 -------------------------EMSTG----------------------------------- 494
                                     |:|..
Zfish   538 INEDVDSHDASDDTDVQDKTEEVNIELSVNKENLPTAQCPPMEKEQNQRETLSMNGEVNSHPPHA 602

  Fly   495 -----KAKNITIKNDKGRLSQAEIDRM---VNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV 551
                 |.|::.:..::....|...||:   ..:..|...:|.:.::|..::||:|..|:..:..:
Zfish   603 KKAKMKVKHVVLPMEETFNQQLPKDRLSAYTEQENKMIQQDRQEKERNNAKNAVEENVYYFRHKL 667

  Fly   552 EQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTKMHQ 609
            |.:....|:..:..:..:..|.|..|| |.....:|:.:.:::.|:.:...|:..:..:
Zfish   668 EGSYQTFLNAQEHQAFSELLNGTENWLYDEGADQDKQTYINRLAEIHKLGLPVENRYRE 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	202/708 (29%)
hsph1	XP_001919957.3	ASKHA_NBD_HSP70_HSPH1	29..408	CDD:466845	154/383 (40%)