Protein Alignment Hsp70Bc and Hspa14

DIOPT Version :10

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 512
• Identity: 179/512 - (34%)
• Similarity: 290/512 - (56%)
• Gaps: 16/512 - (3%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |.|||:.||.|.:||.||:.|:.:::|||.|:|.||:.||:::.|:::|..||.....:..:||.
Mouse     1 MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSEREQVVGLAAKQSRIRHVSSTVV 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ..|:::||...||:..:.:......|:...||.:..::...|:|...||:::.::.:||||||.:
Mouse    66 KVKQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHS 130

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK-NLKGERNVLI 194
            .||....|.|:|||..|.:.|:.|..:|...||.||||:|:||:||.||||:.: :..|:.|||:
Mouse   131 VLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLV 195

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALR 259
            |.|||.:..:|::.::.| ::.|.||....::||..|.:.|..:||.||:|.:|.|:|.|.||:.
Mouse   196 FKLGGTSLSLSVMEVNSG-MYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMM 259

  Fly   260 RLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKM 324
            :|..:||.||.:||:...|...:|:|:|||||...|||||||.||:.||....:.:.:.|.....
Mouse   260 KLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGF 324

  Fly   325 DKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDV 389
            ....|:.:||.|||:||||:|.|:::.|...:|..||.|||.:..|||::|.||.|.:|....|.
Mouse   325 TADDINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDS 389

  Fly   390 LLVDVAP---LSLGIETAGG-VMTKLIERNCRIPCKQTKTFSTYSDNQPG----VSIQVYEGE-R 445
            ::::.:.   |..|::.:|. ..|.|......:|.::..|...     ||    |.:::||.| :
Mouse   390 VMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQA-----PGRVSSVCLELYESEGK 449

  Fly   446 AMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIK 502
            ...|:........|..:.....|:..|.....:..:|.|.|:..:..|||.:.||::
Mouse   450 NSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	178/511 (35%)
Hspa14	NP_056580.2	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	148/376 (39%)