Protein Alignment Hsp70Bc and Hsc70-2

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 641
• Identity: 477/641 - (74%)
• Similarity: 553/641 - (86%)
• Gaps: 12/641 - (1%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            :||||||||||||||||:|:.||||||||||||||||||||.::|||||||||||||||.:||||
  Fly     4 IPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVF 68

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            |||||||||:||.||.||:|.|||||:::.|||||.||:|||.||||||||||||||||:|.||.
  Fly    69 DAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEV 133

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            |||..:.|||:||||||||||||||||||.|||||||||||||||||||||||||||||||||||
  Fly   134 YLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 198

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRR 260
            ||||||||||:|:|||||||||::|||||||||||||||||.|.|||||||:|.|::.|.|||||
  Fly   199 DLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRR 263

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325
            ||||.|||||||||||||::|||||.||.|||:|:||||||||..||||:|:||||:||:|||||
  Fly   264 LRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMD 328

  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390
            |..|||:|||||||||||:|.|||:.|.||.||||||||||||||||||||||:|..|.:|||:|
  Fly   329 KKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLL 393

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALG 455
            |||||||||||||||||||.|:|||.||||||.:.|:||||||..|:|||||||||||||||.||
  Fly   394 LVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLG 458

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            ||:|:||||||||||||||.|||:|:|||||:||:.||||::.|||.|||||||:||||||::||
  Fly   459 TFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEA 523

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAE 585
            |||..||::.|:|:.|:|.||:|::..:|:|:.||:|.|.|.:::.|.|||:....|||.|:.||
  Fly   524 EKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAE 588

  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641
            ||||:..::|..|.|:|||:|:|          |...|:.:.|.|  |.|||||||
  Fly   589 KEEFESHLKECQRICTPIMSKIH----------GGKKGKSSMGKG--SHPTVEEVD 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	475/638 (74%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	312/375 (83%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	475/639 (74%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	312/375 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.740