Protein Alignment Hsp70Bc and CG2918

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Alignment Length: 737
• Identity: 195/737 - (26%)
• Similarity: 327/737 - (44%)
• Gaps: 160/737 - (21%)

  Fly     4 IGIDLGTTYSCVGVYQHG-KVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :.:|||:.:..|||...| .:||..|.:..|.||:.:||.|..|.||:.|:.....:|.:.....
  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYL 87

  Fly    68 KRLIGRKYDDPKIAEDMKHWP-FKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            ..|:|:..|:|.:....|.:| :.:|.|..:..: |..|.::..|:.||:.:.:|.|.|:.|:..
  Fly    88 LDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTV-VFRKSDTDEFSVEELVAQLLVKAKQFAQES 151

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERN----- 191
            :.:.||:.|:|||.||..::|:|...|..:|.|.||::||:..|.||.||:..  :||.|
  Fly   152 VQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFH--RGEINETAQY 214

  Fly   192 VLIFDLGGGTFDVSIL---------TIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFK--R 245
            .|.:|:|......:::         |.:...:.:|.....|..|||.:...||..:||:||.  :
  Fly   215 FLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALK 279

  Fly   246 KYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRN 310
            |.|.|:.::||||.:|...|.|.|..||::||...:|:.|.|..||...|:|.:.|:||.||:..
  Fly   280 KTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPR 344

  Fly   311 TLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLL-----QEFFHGKNLNLSINPDEAVAYG 370
            ..:|:|:||..:.:....|:.::|.||.||:|:||..:     ||.  ||||    |.||:...|
  Fly   345 ATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQEL--GKNL----NADESATMG 403

  Fly   371 AAVQAAILSGDQSGKIQDVLLVDVA--PLSLGIE--TAGGVMTKLIERNC-----RIPCKQTKTF 426
            |..:||.||.  ..|::..::.|..  ||.:..|  ...|...|.::|..     ..|.|:..||
  Fly   404 AVYKAADLSA--GFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITF 466

  Fly   427 STYSDNQPGVSIQVY----EGERAMTKDNNALGTFDLSGIPPAPRGVPQ--------------IE 473
            :.::|:     .:.|    :.:|...::..|||:.:::.:  ..:.|.:              |:
  Fly   467 NKHTDD-----FEFYVNYADLDRYSKEEIAALGSLNVTKV--QLKQVKELLEKSKKELVDNKGIK 524

  Fly   474 VTFDLDANGIL------------------------------------------------------ 484
            ..|.||.:||.
  Fly   525 AYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANA 589

  Fly   485 ---------NVSAKEMSTGK-------------AKN-----ITIKNDKGRLSQAE-IDRMVNEA- 520
                     |..|||....|             |||     :|:|:.....||.: :..:|..|
  Fly   590 GEEPSKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAY 654

  Fly   521 ----EKYA--DEDEKHRQRITSR-NALESYVFNVKQSVEQAPAGKLDEA-DKNSVLDKCNETIRW 577
                .|.|  ::.|:.|.|:.|. ||||:::..|:|.:::....|...| :|..:|.:|:....|
  Fly   655 DQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEW 719

  Fly   578 LDSNTTAEKEE-FDHKMEELTR 598
            |..:....|.| ::.|:.:|.:
  Fly   720 LYEDLEDPKAEIYEEKLAQLKK 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	195/737 (26%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	131/397 (33%)
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	164/619 (26%)
		HYOU1-like_NBD	23..409	CDD:212672	129/394 (33%)
		TAF4	<572..>627	CDD:296797	8/54 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740