Protein Alignment Hsp70Bc and Hsph1

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001011901.1
• Gene: Hsph1 / 288444
• RGDID: 1311609
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 197/615 - (32%)
• Similarity: 326/615 - (53%)
• Gaps: 57/615 - (9%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|:|:|:....:.|.:.|.:|.|||:..:|.|||.::|....|.||..||||...:..|||.
  Rat     1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGPKNRTIGVAAKNQQITHANNTVS 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVE--YKGESKRFAPEEISSMVLTKMKE 126
            ..||..||.::||.|.::.::..:.:|  .:||   :|::  |..|...|:.|:|::|:|||:||
  Rat    66 SFKRFHGRAFNDPFIQKEKENLSYDLVPMKNGG---VGIKVMYMDEDHLFSVEQITAMLLTKLKE 127

  Fly   127 TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK----NLK 187
            |||..|.:.:||.||:||::|.|::|::..||..|.|||.||::|:.||.||.||:.|    |..
  Rat   128 TAENNLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPNAD 192

  Fly   188 GERNVLIF-DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDL 251
            .:..|::| |:|..:|.||....::|.| :|..||.|..|||::||.:||.|...|||.|||.|.
  Rat   193 EKPRVVVFVDMGHSSFQVSACAFNKGKL-KVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDA 256

  Fly   252 RSNPRALRRLRTAAERAKRTLSS-STEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPV 315
            :|..|||.||....|:.|:.:|| ||:..:.|:.....:|...|::|::||||||:|.:....|:
  Rat   257 KSKIRALLRLHQECEKLKKLMSSNSTDLPLNIECFMNDKDVSAKMNRSQFEELCAELLQKIEVPL 321

  Fly   316 EKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            ...:....:...::..|.:|||:||||.|:..:..|| ||:::.::|.|||||.|.|:|.||||
  Rat   322 HLLMEQTHLKTEEVSAIEIVGGATRIPAVKERIARFF-GKDVSTTLNADEAVARGCALQCAILS- 384

  Fly   381 DQSGKIQDVLLVDVAPLSLGI-------ETAGGVMTKLIERNCRIPCKQTKTF---------STY 429
             .:.|:::..:.|..|..:.:       ||.|  :.::..||...|..:..||         :.|
  Rat   385 -PAFKVREFSVTDAVPFPISLVWNHDSEETEG--VHEVFSRNHAAPFSKVLTFLRRGPFELEAFY 446

  Fly   430 SDNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRG-VPQIEVTFDLDANGILNVSAKEMST 493
            ||.|            |:......:|.|.:..:.....| ..:::|...::.:||..:|...|
  Rat   447 SDPQ------------AVPYPEAKIGRFVVQNVSAQKDGEKSKVKVKVRVNTHGIFTISTASM-- 497

  Fly   494 GKAKNITIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGK 558
              .:.:..:.:.|...:|::: ..|:....:.:.:|:.|:..|....:..|....|...|:|...
  Rat   498 --VEKVPTEEEDGSSVEADME-CPNQKPAESSDVDKNIQQDNSEAGTQPQVQTDGQQTSQSPPSP 559

  Fly   559 LDEADKNSV--LDKCNETIRWLDSNTTAEK 586
            ...:::|.:  .||.||  :.:|....|:|
  Rat   560 ELTSEENKIPDADKANE--KKVDQPPEAKK 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	196/614 (32%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	152/385 (39%)
Hsph1	NP_001011901.1	HSPH1_NBD	2..384	CDD:212689	152/386 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	500..585		16/87 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	801..858

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810