DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hsp70Bc and SLC9C2

DIOPT Version :9

Sequence 1:NP_650209.1 Gene:Hsp70Bc / 48583 FlyBaseID:FBgn0013279 Length:641 Species:Drosophila melanogaster
Sequence 2:XP_011507728.1 Gene:SLC9C2 / 284525 HGNCID:28664 Length:1129 Species:Homo sapiens


Alignment Length:277 Identity:49/277 - (17%)
Similarity:94/277 - (33%) Gaps:111/277 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 EISSMVLTKMK-----------ETAEAYLGESI----TDAVITVPAYFNDSQRQATKDAGH---- 160
            ||:.::|.|:|           .|.:.||...|    .|.:|.   :|.:..:.|..|:|.    
Human   835 EINKVLLKKLKALNNFPKAIPPPTPDIYLHNIIWLEGKDVLID---FFKERAKLACFDSGDTICK 896

  Fly   161 -----------IAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSL 214
                       |:|:.:|..:: ||     :|::.|.:.:|         |:.|          :
Human   897 GGEMPQGIYLIISGMAILHSLS-PT-----FGIESNQRCDR---------GSRD----------M 936

  Fly   215 FEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEAT 279
            |....|.||           ::..|:...||:.:..:                   ...:|.:|.
Human   937 FTEFCTTGD-----------IIGELSCLLKREIEYTV-------------------ICETSLQAC 971

  Fly   280 -IEIDALFEGQD---------FYTKVSRAR----FEELCAD---------LFRNTLQPVEKALND 321
             |.::.|:||.|         .:.|::.:.    ||....|         :|.........:.:|
Human   972 FISLEDLYEGFDAFWPSLEYKIWLKLALSTAYQYFESSLIDEDLRFQNCVMFNQAYVETLSSYSD 1036

  Fly   322 AKMDKGQIHDIVLVGGS 338
            ..:|...:..:::|.||
Human  1037 MIIDNMTMKFVIIVYGS 1053

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hsp70BcNP_650209.1 PTZ00009 2..641 CDD:240227 49/277 (18%)
HSPA1-2_6-8-like_NBD 3..379 CDD:212675 49/277 (18%)
SLC9C2XP_011507728.1 Na_H_Exchanger 98..380 CDD:294713
Ion_trans 638..>731 CDD:278921
CAP_ED 873..980 CDD:237999 27/164 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0443
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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